# Latest **URL:** https://www.rapamycin.news/latest.md [Latest](https://www.rapamycin.news/latest.md) · [Categories](https://www.rapamycin.news/categories.md) · [Tags](https://www.rapamycin.news/tags.md) --- ## [\[REFERENCE\] Master list of all places to get blood tests](https://www.rapamycin.news/t/reference-master-list-of-all-places-to-get-blood-tests/12897)
**Author:** [@AlexKChen](https://www.rapamycin.news/u/AlexKChen)\ **Replies:** 35\ **Last updated:** [November 1, 2026, 11:41pm UTC](https://www.rapamycin.news/t/reference-master-list-of-all-places-to-get-blood-tests/12897 "2026-11-01T23:41:08Z")
GoodLabs - (The lowest price vendor we’ve found. a great place to start, for low price testing, or free if you donate blood. You can choose quest or labcorp as a place to get your tests done). I have a list of all their prices here. https://www.ultalabtests.com uses Quest Genova Diagnostics (has friction like requiring doctor’s Rx). Life Extension Lab tests \[ uses labcorp\] https://… --- ## [New to Rapamycin? Start Here](https://www.rapamycin.news/t/new-to-rapamycin-start-here/5438)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 45\ **Last updated:** [October 27, 2025, 5:13pm UTC](https://www.rapamycin.news/t/new-to-rapamycin-start-here/5438 "2025-10-27T17:13:15Z")
Rapamycin is considered by most longevity scientists and geroscience researchers to be the “gold standard” of longevity drugs; with healthy lifespan improvement typically in the range of 15% to 30%, and as high as 37% when combined with another longevity drug “Acarbose”. While these results have been in animals, there are many early indications that these benefits may also translate to people. B… --- ## [Welcome to Rapamycin News, The Longevity Drug User Group](https://www.rapamycin.news/t/welcome-to-rapamycin-news-the-longevity-drug-user-group/7)
**Author:** [@system](https://www.rapamycin.news/u/system)\ **Replies:** 11\ **Last updated:** [April 19, 2025, 7:07pm UTC](https://www.rapamycin.news/t/welcome-to-rapamycin-news-the-longevity-drug-user-group/7 "2025-04-19T19:07:57Z")
This website is for people interested in living longer, and healthier lives using the latest longevity medicine and geroscience information. Here you will find real-world, personal experiences of people who are testing rapamycin (sirolimus) and other medications and therapies that lab and clinical research is suggesting could have a significant positive impact on healthy lifespans. While our mai… --- ## [Are sugar-free energy drinks pro or anti longevity? What are the best energy drinks? concerned about artificial sweeteners](https://www.rapamycin.news/t/are-sugar-free-energy-drinks-pro-or-anti-longevity-what-are-the-best-energy-drinks-concerned-about-artificial-sweeteners/5289)
**Author:** [@AlexKChen](https://www.rapamycin.news/u/AlexKChen)\ **Replies:** 32\ **Last updated:** [November 6, 2026, 6:38pm UTC](https://www.rapamycin.news/t/are-sugar-free-energy-drinks-pro-or-anti-longevity-what-are-the-best-energy-drinks-concerned-about-artificial-sweeteners/5289 "2026-11-06T18:38:48Z")
The appetite suppressant effects are IMO the most important, since a reduction of even 200 calories a day is enough to induce the effects of mild calorie restriction (see CALERIE study and reduction of 15% of total calorie intake) They single-handedly address half of the nutritional deficiencies vegans have (just not choline) But the main concern is sucralose. That said, occasional use can suppr… --- ## [Buck Institute Aging Event - November 12, 2026 (Novato)](https://www.rapamycin.news/t/buck-institute-aging-event-november-12-2026-novato/27370)
**Author:** [@Sfcomms](https://www.rapamycin.news/u/Sfcomms)\ **Replies:** 3\ **Last updated:** [November 6, 2026, 6:11pm UTC](https://www.rapamycin.news/t/buck-institute-aging-event-november-12-2026-novato/27370 "2026-11-06T18:11:04Z")
Anyone going to the Buck aging event next week? --- ## [Can statins be pro-healthspan/longevity even if they don't increase mice lifespan? Interaction with metformin / rapamycin/ etc?](https://www.rapamycin.news/t/can-statins-be-pro-healthspan-longevity-even-if-they-dont-increase-mice-lifespan-interaction-with-metformin-rapamycin-etc/6301)
**Author:** [@AlexKChen](https://www.rapamycin.news/u/AlexKChen)\ **Replies:** 149\ **Last updated:** [November 6, 2026, 5:45pm UTC](https://www.rapamycin.news/t/can-statins-be-pro-healthspan-longevity-even-if-they-dont-increase-mice-lifespan-interaction-with-metformin-rapamycin-etc/6301 "2026-11-06T17:45:30Z")
Mice just don’t die of heart disease like humans - this is why ITP went negative on them (even though, like, they were harmless). Humans uniquely have high LDL levels… My impression (I’ve seen a lot) is that statins are on the marginal pro-longevity, but with very small effect size in the ultra-healthy https://www.pnas.org/doi/10.1073/pnas.0907117106 The main concern is that statins reduce Coenz… --- ## [Vaccination Is Becoming a Longevity Intervention, Not Just Infection Control](https://www.rapamycin.news/t/vaccination-is-becoming-a-longevity-intervention-not-just-infection-control/27319)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 4\ **Last updated:** [November 6, 2026, 5:39pm UTC](https://www.rapamycin.news/t/vaccination-is-becoming-a-longevity-intervention-not-just-infection-control/27319 "2026-11-06T17:39:32Z")
This editorial from the Editor-in-Chief of Age and Ageing and a co-author, is written to launch the journal’s new online collection of vaccine research. It summarizes thirteen previously published papers across three themes. On uptake, it notes that influenza vaccination rates are falling internationally and that successful programs combine clinician education, centralized reminders and easy ac… --- ## [Science Article: Castration improves longevity](https://www.rapamycin.news/t/science-article-castration-improves-longevity/27361)
**Author:** [@WJ\_PhD](https://www.rapamycin.news/u/WJ_PhD)\ **Replies:** 9\ **Last updated:** [November 6, 2026, 4:24pm UTC](https://www.rapamycin.news/t/science-article-castration-improves-longevity/27361 "2026-11-06T16:24:40Z")
I realize this may be controversial and unpopular but it does seem to indicate that older testes have more of an impact on male longevity. It could also help explain why women in the US outlive men by ~ 6 years. https://www.science.org/content/article/castration-extends-life-span-surprising-way-mouse-study-suggests? Castration extends life span, but in a surprising way, mouse study suggests S… --- ## [Blood Levels of the Mushroom Antioxidant Ergothioneine Track With a 44% Lower Dementia Risk in Older Japanese Adults](https://www.rapamycin.news/t/blood-levels-of-the-mushroom-antioxidant-ergothioneine-track-with-a-44-lower-dementia-risk-in-older-japanese-adults/27092)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 6\ **Last updated:** [November 6, 2026, 2:41pm UTC](https://www.rapamycin.news/t/blood-levels-of-the-mushroom-antioxidant-ergothioneine-track-with-a-44-lower-dementia-risk-in-older-japanese-adults/27092 "2026-11-06T14:41:41Z")
In a 11-year follow-up of 1,344 dementia-free adults aged 65 and over in Hisayama, Japan, people in the top quarter of serum ergothioneine had about 44% lower adjusted risk of developing any dementia than those in the bottom quarter. The pattern held for Alzheimer’s disease and was steepest, though statistically imprecise, for non-Alzheimer dementia. Adjusting for vegetable intake, cardiovascul… --- ## [TRT therapy alongside Rapamycin](https://www.rapamycin.news/t/trt-therapy-alongside-rapamycin/1951)
**Author:** [@hobbyfarmer](https://www.rapamycin.news/u/hobbyfarmer)\ **Replies:** 17\ **Last updated:** [November 6, 2026, 2:12pm UTC](https://www.rapamycin.news/t/trt-therapy-alongside-rapamycin/1951 "2026-11-06T14:12:06Z")
Anyone know if TRT negates the shutdown of mTOR1 by Rapamycin. Am I flipping off the switch with RAPA only to turn it back on with the TRT? --- ## [A drug-free treatment for diabetes and obesity is within reach, say experts (and it's not exercise)](https://www.rapamycin.news/t/a-drug-free-treatment-for-diabetes-and-obesity-is-within-reach-say-experts-and-its-not-exercise/27369)
**Author:** [@rickyf](https://www.rapamycin.news/u/rickyf)\ **Replies:** 0\ **Last updated:** [November 6, 2026, 1:58pm UTC](https://www.rapamycin.news/t/a-drug-free-treatment-for-diabetes-and-obesity-is-within-reach-say-experts-and-its-not-exercise/27369 "2026-11-06T13:58:57Z")
A new high-tech device reduced blood sugar levels and body weight in early trials on mice Steph Santos Paulo Published: October 30, 2026 at 10:00 am Scientists have invented a wireless electronic device that removes excess sugar from the blood and could, one day, offer a drug-free treatment for diabetes and obesity. The device, which was developed by a team of researchers in Switzerland and F… --- ## [Grey Hair turning Black again after 10 years](https://www.rapamycin.news/t/grey-hair-turning-black-again-after-10-years/6066)
**Author:** [@Steven\_Ow](https://www.rapamycin.news/u/Steven_Ow)\ **Replies:** 69\ **Last updated:** [November 6, 2026, 12:45pm UTC](https://www.rapamycin.news/t/grey-hair-turning-black-again-after-10-years/6066 "2026-11-06T12:45:19Z")
I am 68 and have been on Rapamycin for 2 months, 6mg every week. I have been solid grey hair for over 10 years so I was amazed to see some black hair growing in again. I will post a picture when I get a chance. Is anyone else expericing the same effects? I feel great and have lots of energy, blood presssure droping, average sleeping heart rate has been droping as well. --- ## [A Week of Wearing Your Smartwatch Could Flag Hidden High Blood Pressure](https://www.rapamycin.news/t/a-week-of-wearing-your-smartwatch-could-flag-hidden-high-blood-pressure/27360)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 1\ **Last updated:** [November 6, 2026, 12:07pm UTC](https://www.rapamycin.news/t/a-week-of-wearing-your-smartwatch-could-flag-hidden-high-blood-pressure/27360 "2026-11-06T12:07:30Z")
Google researchers trained an AI model on wrist pulse waveforms (photoplethysmography) and motion signals from a Pixel Watch 3 to flag likely hypertension without any cuff calibration. In a prospective five-site US study, 196 adults without heart disease or blood pressure medication wore the watch for about a week and completed 24-hour ambulatory blood pressure monitoring, the clinical gold sta… --- ## [Regional and person-associated variation in age-related intronic RNA across human tissues (preprint 4th November 2026)](https://www.rapamycin.news/t/regional-and-person-associated-variation-in-age-related-intronic-rna-across-human-tissues-preprint-4th-november-2026/27351)
**Author:** [@John\_Hemming](https://www.rapamycin.news/u/John_Hemming)\ **Replies:** 3\ **Last updated:** [November 6, 2026, 11:49am UTC](https://www.rapamycin.news/t/regional-and-person-associated-variation-in-age-related-intronic-rna-across-human-tissues-preprint-4th-november-2026/27351 "2026-11-06T11:49:04Z")
chatGPT(6Max): The paper makes a potentially valuable observational contribution through its regional map of age-associated intronic RNA and its analysis of differences between people. Its findings support further investigation of RNA processing in ageing, while leaving the underlying mechanism unresolved. This assessment concerns Regional and person-associated variation in age-related introni… --- ## [A system for storing medication to safely extend its shelf life up to over 10 years](https://www.rapamycin.news/t/a-system-for-storing-medication-to-safely-extend-its-shelf-life-up-to-over-10-years/27362)
**Author:** [@cl-user](https://www.rapamycin.news/u/cl-user)\ **Replies:** 6\ **Last updated:** [November 6, 2026, 9:04am UTC](https://www.rapamycin.news/t/a-system-for-storing-medication-to-safely-extend-its-shelf-life-up-to-over-10-years/27362 "2026-11-06T09:04:43Z")
As many of us are stocking up on key medications, proper long-term storage is essential. I came up with this simple but effective method after extensive discussions with Claude Opus 5.5 High. Below are a few photos showing how the setup looks for a 3 months pack, followed by the detailed rationale behind it: The silica beads: Amazon.com: Wisesorb \[Net Weight 8LBS\] Blue Indicating Sil… --- ## [Ketone Esters Blunt Inflammaging: Selective Suppression of Age-Associated B Cells Preserves Immune Competence](https://www.rapamycin.news/t/ketone-esters-blunt-inflammaging-selective-suppression-of-age-associated-b-cells-preserves-immune-competence/27368)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 1\ **Last updated:** [November 6, 2026, 7:32am UTC](https://www.rapamycin.news/t/ketone-esters-blunt-inflammaging-selective-suppression-of-age-associated-b-cells-preserves-immune-competence/27368 "2026-11-06T07:32:02Z")
Aging is characterized by a progressive decline in immune function and a simultaneous increase in chronic, low-grade inflammation, largely driven by the accumulation of age-associated B cells. These cells contribute to autoimmune pathology by secreting pro-inflammatory cytokines and autoantibodies. This preclinical murine study investigated the immunomodulatory effects of a 15-week dietary inte… --- ## [ADHD Carries Heavy Mortality Burden, But Treatment Closes the Gap](https://www.rapamycin.news/t/adhd-carries-heavy-mortality-burden-but-treatment-closes-the-gap/27363)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 1\ **Last updated:** [November 6, 2026, 6:53am UTC](https://www.rapamycin.news/t/adhd-carries-heavy-mortality-burden-but-treatment-closes-the-gap/27363 "2026-11-06T06:53:16Z")
Attention-deficit hyperactivity disorder is highly correlated with adverse life outcomes and premature mortality. A comprehensive systematic review and meta-analysis of 19 studies encompassing over 15.9 million participants evaluated the association between this disorder and various mortality causes. The data demonstrate that individuals with this condition face a 71% elevated risk of all-cause… --- ## [DORAs, Sleeping Pills, & Weight Loss](https://www.rapamycin.news/t/doras-sleeping-pills-weight-loss/17521)
**Author:** [@ageless64](https://www.rapamycin.news/u/ageless64)\ **Replies:** 55\ **Last updated:** [November 6, 2026, 6:03am UTC](https://www.rapamycin.news/t/doras-sleeping-pills-weight-loss/17521 "2026-11-06T06:03:33Z")
Thoughts? Analysis: Suvorexant, Sleep & Metabolism A. Executive Summary In this episode, sleep scientist Dr. Matthew Walker reviews a recent study published in the journal iScience (2024) that investigates the metabolic effects of Suvorexant (brand name Belsomra), a dual orexin receptor antagonist (DORA) used for insomnia. The study, conducted by researchers at the University of Tsukuba, invo… --- ## [BPH Prostate improvement?](https://www.rapamycin.news/t/bph-prostate-improvement/11640)
**Author:** [@sudiki](https://www.rapamycin.news/u/sudiki)\ **Replies:** 37\ **Last updated:** [November 6, 2026, 2:22am UTC](https://www.rapamycin.news/t/bph-prostate-improvement/11640 "2026-11-06T02:22:14Z")
new to site but I didn’t come across any posts so far on improved prostate health (BPH). Any input/comments? thx --- ## [Imeglimin: An Approved Diabetes Pill Just Made Old Mice Stronger](https://www.rapamycin.news/t/imeglimin-an-approved-diabetes-pill-just-made-old-mice-stronger/26307)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 40\ **Last updated:** [November 6, 2026, 2:11am UTC](https://www.rapamycin.news/t/imeglimin-an-approved-diabetes-pill-just-made-old-mice-stronger/26307 "2026-11-06T02:11:39Z")
Sarcopenia, the age-related loss of muscle mass and strength, has no approved drug treatment anywhere in the world. This study reports that imeglimin, a first-in-class oral antidiabetic already licensed in Japan under the name Twymeeg, preserved skeletal muscle in two independent mouse models of muscle loss. In obese mice, six weeks of treatment restored shrunken fast-twitch fibres in the exten… --- ## [Estrogen Exposure Across the Lifespan Shields the Aging Female Brain from Vascular Damage](https://www.rapamycin.news/t/estrogen-exposure-across-the-lifespan-shields-the-aging-female-brain-from-vascular-damage/27364)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 0\ **Last updated:** [November 6, 2026, 1:12am UTC](https://www.rapamycin.news/t/estrogen-exposure-across-the-lifespan-shields-the-aging-female-brain-from-vascular-damage/27364 "2026-11-06T01:12:44Z")
This study investigates the relationship between lifetime estrogen exposure and late life brain health in a cohort of 352 cognitively normal 70 year old women. Researchers analyzed endogenous estrogen, measured by reproductive lifespan, alongside exogenous estrogen from oral contraceptives and menopausal hormone therapy. Using magnetic resonance imaging, the team evaluated cerebral small vessel… --- ## [Is Dayvigo（lemborexant) a safe sleep pill?](https://www.rapamycin.news/t/is-dayvigo-lemborexant-a-safe-sleep-pill/21548)
**Author:** [@Rika\_Qu](https://www.rapamycin.news/u/Rika_Qu)\ **Replies:** 64\ **Last updated:** [November 6, 2026, 12:42am UTC](https://www.rapamycin.news/t/is-dayvigo-lemborexant-a-safe-sleep-pill/21548 "2026-11-06T00:42:07Z")
Dayvigo® (lemborexant), Eisai’s dual orexin receptor antagonist, was approved in China in recently. I am wondering if it’s the safest drug we can get on the market? In the past I tried several other sleep drugs and they don’t work very well on me. I tried a ‘safe’ pill Ramelteon and it halves my deep sleep duration according to the OURA ring. I also tried low dose of trazodone and it made me dr… --- ## [Planned Server Downtime / Software Upgrade Completed](https://www.rapamycin.news/t/planned-server-downtime-software-upgrade-completed/27287)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 11\ **Last updated:** [November 5, 2026, 10:49pm UTC](https://www.rapamycin.news/t/planned-server-downtime-software-upgrade-completed/27287 "2026-11-05T22:49:40Z")
Just wanted to let people know that there will be some scheduled website downtime this week as we cut over to a new server with the latest software on it. So, on Wednesday Nov 4th, and Thursday, November 5th the site will be put into “Read-only” mode starting around 6am in the morning. When we’re finished the work, we’ll remove the “read-only” mode and put it into live mode. On the new software… --- ## [Stiff Arteries Softened: Pulse Wave Velocity Falls 13 Percent With a Daily Longevity Supplement Blend](https://www.rapamycin.news/t/stiff-arteries-softened-pulse-wave-velocity-falls-13-percent-with-a-daily-longevity-supplement-blend/27359)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 2\ **Last updated:** [November 5, 2026, 7:24pm UTC](https://www.rapamycin.news/t/stiff-arteries-softened-pulse-wave-velocity-falls-13-percent-with-a-daily-longevity-supplement-blend/27359 "2026-11-05T19:24:43Z")
A six-month randomized, double-blind trial from the University of Surrey tested NOVOS Core, a daily 15 g powder combining twelve ingredients including glycine, calcium alpha-ketoglutarate, glucosamine, magnesium malate, fisetin, pterostilbene and low-dose lithium, in 61 healthy adults over 40. Among the 43 who finished, the supplement raised brachial flow-mediated dilation, a measure of how wel… --- ## [Lower IGF-1, Quicker Minds: Aged Beagles Respond Faster After One Octreotide Shot](https://www.rapamycin.news/t/lower-igf-1-quicker-minds-aged-beagles-respond-faster-after-one-octreotide-shot/27358)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 1\ **Last updated:** [November 5, 2026, 6:56pm UTC](https://www.rapamycin.news/t/lower-igf-1-quicker-minds-aged-beagles-respond-faster-after-one-octreotide-shot/27358 "2026-11-05T18:56:44Z")
Researchers at Loyal Animal Health tested whether lowering insulin-like growth factor 1 (IGF-1) late in life changes how aged dogs think. Twenty-eight laboratory beagles aged 7 to 15, all experienced with cognitive testing, received a single injection of long-acting octreotide, a somatostatin analog that suppresses growth hormone, or saline. Octreotide cut circulating IGF-1 by about 29 percent … --- ## [Hazel Szeto, SS-31 peptide, the World's First FDA-Approved Mitochondria-targeted Drug (Longevity Summit, 2025)](https://www.rapamycin.news/t/hazel-szeto-ss-31-peptide-the-worlds-first-fda-approved-mitochondria-targeted-drug-longevity-summit-2025/22586)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 389\ **Last updated:** [November 5, 2026, 6:54pm UTC](https://www.rapamycin.news/t/hazel-szeto-ss-31-peptide-the-worlds-first-fda-approved-mitochondria-targeted-drug-longevity-summit-2025/22586 "2026-11-05T18:54:03Z")
I found this to be a very interesting presentation by Hazel Szeto. She’s a researcher out of Cornell who discovered and refined the SS-31 Peptide that has now gotten FDA approval as part of Stealth Biosciences. And of course the SS stands for Szeto and Schiller (the two researchers) and there were 30 attempts before they arrived at the final version of the peptide. Hazel is an extremely engaging … --- ## [E/A ratio on echocardiography? What are ways to improve it?](https://www.rapamycin.news/t/e-a-ratio-on-echocardiography-what-are-ways-to-improve-it/27342)
**Author:** [@AlexKChen](https://www.rapamycin.news/u/AlexKChen)\ **Replies:** 7\ **Last updated:** [November 5, 2026, 6:47pm UTC](https://www.rapamycin.news/t/e-a-ratio-on-echocardiography-what-are-ways-to-improve-it/27342 "2026-11-05T18:47:52Z")
And what values have you gotten? --- ## [Just a little humor](https://www.rapamycin.news/t/just-a-little-humor/12176)
**Author:** [@ng0rge](https://www.rapamycin.news/u/ng0rge)\ **Replies:** 485\ **Last updated:** [November 4, 2026, 11:14pm UTC](https://www.rapamycin.news/t/just-a-little-humor/12176 "2026-11-04T23:14:12Z")
I haven’t been on this forum all that long but I’m a quick learner and just wanted to pass on some of my observations and tips for new users. The quickest way to make friends here is: 1) Attack David Sinclair. 2) Never refer to Peter Attia as “that muscle bound geek” but it is OK to disagree with his obsession with protein intake. 3) Post about Bryan Johnson’s…“johnson” (The underground press … --- ## [Wall Street Journal Says No More Cheap Overseas Prescriptions Shipped to USA?](https://www.rapamycin.news/t/wall-street-journal-says-no-more-cheap-overseas-prescriptions-shipped-to-usa/26737)
**Author:** [@lillycat](https://www.rapamycin.news/u/lillycat)\ **Replies:** 270\ **Last updated:** [November 4, 2026, 8:39pm UTC](https://www.rapamycin.news/t/wall-street-journal-says-no-more-cheap-overseas-prescriptions-shipped-to-usa/26737 "2026-11-04T20:39:06Z")
Ola Friends! YIKES! WSJ had an article yesterday saying that new regulations are being enacted starting October 22, 2026 that will shut down USA citizens ability to order prescription drugs from Canada, and other overseas sources. Did anyone see this? Will this shut down our rapamycin sources from places such as India? I’m worried! --- ## [Losing Visceral Fat May Matter More Than Gaining Lean Mass for Blood Sugar](https://www.rapamycin.news/t/losing-visceral-fat-may-matter-more-than-gaining-lean-mass-for-blood-sugar/27356)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 0\ **Last updated:** [November 4, 2026, 7:15pm UTC](https://www.rapamycin.news/t/losing-visceral-fat-may-matter-more-than-gaining-lean-mass-for-blood-sugar/27356 "2026-11-04T19:15:13Z")
Researchers at Pennington Biomedical Research Center analyzed 59,269 UK Biobank participants with both DXA and MRI body composition scans. They asked why higher fat-free mass, usually considered metabolically protective, keeps turning up in large studies as a risk factor for insulin resistance. Absolute fat-free mass and fat-free mass scaled to height were linked to more metabolic syndrome and … [Next page](https://www.rapamycin.news/latest.md?page=1)