#151

There is no such thing as a bubble before it has happened.

… "People see bubbles where there are none,” Fama told the group, in an appearance that was live-streamed.

To bolster his point, Fama cited a celebrated experiment in a faculty lounge at Stanford. A bunch of professors were presented with charts of agricultural prices. Their charge was to identify any bubbles. The profs did so, and then learned that the data were randomly generated. No patterns existed.

Bubbles are apparent only after the fact, Fama contended. “The way I interpret it is: You must be able to predict the end of it,” he said. “A bubble has to be something with a predictable ending.” And he added: “What’s the testable proposition?” …

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#152

At the end of the day, I don’t care what anyone’s opinion of Bryan Johnson is. I am only interested in the protocols he is doing and what his results are from them to see if I can learn something from it.

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#153

Good trailer, not much traction yet (94K views).

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#154

Just wondering a few things about Bryan Johnson’s protocol. Baby Aspirin 3X a week? Why? Metformin does seems very high, he eats clean?

#155

Bryan Johnson recently stopped Rapamycin and posted on X/Twtter about it:

https://x.com/bryan_johnson/status/1857131261980270933

From his recent blog on BluePrint: In September I stopped Rapamycin, based on concerns around its metabolic side-effects observed in my lab results (including increased cholesterol, blood sugar and RHR); the data here showed Rapamycin increased biological aging according to two clocks, while ineffective according to the others.

Thoughts on this?

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#156

Welcome to the forum!
There’s a long thread about this here:

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#157

Hello!

I have a commercial design background. A lot of Showmanship with Bryan J.

I think he blew off rapamycin without good reasoning. But, fine for him.

By biological age based on glycans and methylation is 15 to 20 years better. Pretty sure it is the rapamycin for 4 years.

Welcome to the dialog.

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#158

a more ambitious film would recognize this material, foremost, as a story of familial estrangement and religious seeking, and more fully integrate these elements into its narrative DNA. For all its anti-aging trappings, Smith’s movie is most intriguing when detailing Johnson’s crippling depression at the height of his professional success, his decision to leave the Mormon church, his ongoing estrangement from two other children, and other personal stories.

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#159

:crown:

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#160

Is the documentary any good? Does it actually discuss his protocols or is it more or less just about his life and how we got to where he is now?

I am a little more interested in the protocols than a biography, but that’s just me

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#161

I think it was more about his mission and life, and less about his protocols.

Those are mentioned, but there is nothing in there you don’t already know if you’ve followed him at all. I really like the guy and I fast forwarded through some sections if that tells you anything.

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#162

I saw it yesterday. It is his very personal story and more about himself, his background and his “movement” than deep diving in the protocol. But I found it interesting to learn about his story, as he presents it. So no, not much about his protocol. It is aiming at the public, not at avid biohackers or health optimizers. The general audience does not know what red yeast rice is or what lutein is. It would not be relevant for most viewers if they started to dive deep into specific supplements. It does not mention specific supplements but Rapamycin is mentioned once.

Yes, he sells supplements, and some might hold that against him. I don’t. He is an entrepreneur going all in on longevity. He puts his name on a line of supplements. A supplement industry where fraud is a big part of the game. The industry needs players that are honest and actually sell what is stated on the label of the bottles, full disclosure, third party testing and scientifically-backed dosages. I don’t buy the blueprint line of wellness products. I create my own regimen of supplements from brands that I trust.

But I think he is one of the good guys in the industry.

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#163

He did quite well with the concept of a black swan, but actually there are black swans in Australia and a town in Devon keeps them as well (Dawlish).

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#164

I also genuinely think he’s a good guy, so I may watch it anyway at some point.

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#165

As long as you know what to expect, I think you’ll enjoy it. I don’t regret the time spent.

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#166

I agree, The cynics think it is only about $$ but no business person in their right mind would spend the money he has to insure product purity. I don’t think he is making money at this at the moment

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#167

Yes - I do agree with that. I do trust his products more than most supplement companies. His credibility would be destroyed if they didn’t test (e.g. via consumerlab.com) to be good products with the content claimed.

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#168

Hello,
I watched the Bryan Johnson movie. It focused a lot on Bryan and his story. I would have liked to hear more health tips. He spent time discussing the bonding experience with his father and son and sharing plasma. On a higher level, I really think it’s fantastic that Bryan is getting so many people to think about health and longevity. I kind of wish he wasn’t selling supplements and was instead just sharing data and information. He could have become a trustworthy source of consumer information. Nonetheless, it’s great that more people are thinking about longevity.

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#169

yes, agree. After wondering for years if the stuff I buy off of Amazon is the real deal or worse full of heavy metals, it is refreshing to not worry about the quality. He recently stated that he brought all his own products to India to eat because he trusts them more than any other food for safety.

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#170

Would love to hear a debate between these two. Somebody make this happen