Just wanted to show what a typical “shredded” face look at 45 when you have Bryans bodyfat and how loosing bodyfat makes your body sexier but face look instantly older:
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To be honest, good for Bryan… truly hope he can shed some light onto slowing the aging process in skin, muscle, organs and mind/memory. Just thought the foundation looked a bit heavy in the pics. Recently, started using sun screen first time ever and it has a tint - so I am no better now. LOL
Your series of photos of loss of body weight (shredding) and the effects on your face is interesting. I have noticed as my body fat has diminished (DEXA of 25 BMI - normal) my face plump-ness - which tends to make you look younger - is lessened too.
As you pointed out… I believe that rapamycin, at least in my case - has gotten rid of all the extra adipose tissue everywhere including my face. Healthy, but also looking older in the face a bit more than your body. Hmmmm… ?
Also, that old man slit belly button development… at least with rapamycin - it returns you to a sexy round belly button. 
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LaraPo
#351
I think that for a 45 year old his skin is very good in any picture. Almost no wrinkles, and no deep wrinkles. He definitely looks good and healthy.
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jakexb
#352
His project is so interesting, but I have to say even as someone really interested in this stuff, his persona/style is odd enough to be offputting for a lot of people.
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blsm
#353
I thought Bryan was handsome to begin with in his self described unhealthy years. I appreciate what he is doing but the religious connotations in some of his twitter posts I could personally do without.
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Overly aggressive treatments done too frequently. It’s a thing. There are lots of disaster stories and support groups for the victims of practitioners who oversold and didn’t know how to use their devices. But in this case, it’s self-inflicted.
The collagen building response to insult is blunted after 30, so repeatedly wounding the skin does not improve it after a certain age.
I think at this point the only thing that will truly improve the skin at age 45 or beyond aside from rx retinoids and high UVA protection is stem cells, i.e. autologous fat transfer. He doesn’t have enough body fat for that now. If he gained 20 lbs, he could have enough for a decent harvest. Then he’d have to repeat the procedure every year or two, alternating with biostimulators like PLLA or PCL. It’s affordable for someone like him, maybe not so much for people with normal incomes.
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AnUser
#355
It looks like bad lighting to me with skin cream.
He was raised mormon so I guess it’s his rebellious side.
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jakexb
#356
Totally, I think some sculptra would do him wonders. His skin tone is great, just could use some volume.
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Jin
#357
I feel exactly the same. Im not trying to set any age health fitness records in my 60s. Just want to be strong and fit and run 10kms in the morning when i feel like it and not have pain peppered all over 
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AnUser
#358
Bryan is increasing his caloric intake to 2250 from 2000 to increase ‘facial fat’. I guess he no longer wants to look 20 and 80 at the same time? How much does appearance matter?
https://twitter.com/bryan_johnson/status/1683531108078727168
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AnUser
#359
So is anyone here using Blueprint recipes? Following Blueprint diet?
Thoughts?
I’m thinking of trying nutty pudding first.
There is likely to be some overlap with everyone, but i have not learnt from blueprint although i have some overlap. Eg i eat some ginger and chocolate
LaraPo
#361
I eat most foods on Blueprint. Instead of chocolate I eat cacao to avoid as much sugar as I can.
I like a dark mint chocolate which comes in thin pieces which you can break into 40-50 pieces and eat quite slowly. I use a sharp knife to create grooves in the chocolate so it breaks into squares approx 1-2mm by 1-2mm.
It does quite well with some form of tisane. I have been monitoring my copper levels and I supplement with copper, but cocoa is a good copper source as well. (much nicer than the blue tablets).
Cocoa is also good for other things.
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I think anyone whose control over his macros, micros, and calories savors of anal retentiveness Olympics will manifest that acute compulsiveness in his face somehow. The guy looks and sounds like a different species and I think he has crossed the Rubicon on that front with this routine drastic interventions. He has a posture coach and I’ll honestly steal the tips for my daughter who has horrible posture but I kept wondering, while watching the video, how long before he gets a voice coach? He sounds like an uber dorky 11 year old who lives in his own meticulously handcrafted mind blowing Minecraft world and whose vocal cords just happened to overnight age to those of a 45 year old. A man who’ll always have to pay for sex one way or another. And maybe he doesn’t mind because he’ll always afford it but man o man.
FYI I don’t mean to hate on the guy. I love what he’s doing as he’s proving first and foremost that we won’t die from taking the supplements we are, only get healthier. But the harder he tries the deeper anonymous bystanders to his open source experiment will end up trying to fill in that gaping uncanny valley he’s dug himself into with suggestions, from upping his caloric intake to toning down the ginger in his hair dye to… I guess, working with an accent coach. Kind of makes me sad to look at or listen to him.
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Have you looked at doing your own Mesotherapy? I am sure you know of Profile, some ppl DIY at home with BAP technique, which doesn’t look too hard…
Neo
#368
Anyone know or have thoughts on the rationale for the
13mg then 6mg then 13, then 6 and so on?
