#583

I think his major problem with face is low body fat percentage. And for someone in his mid forties and having BF of 6% his face is looking quite good. He was never a good looking guy and it shouldn’t be fair to judge his appearance from beauty standards. But his facial skin and musculature seem quite improved lately. Maybe not 18, but i would say he looks in his late thirties. Give him some suntan, better hairdo and he would pass for someone even younger IMO.

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#584

Bryan Johnson… is likeable?

Also if superintelligence is here soon I might as well have that McDonald’s toy :rofl:

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#585

Mostly younger people, I’d have come in around 45 minutes and maybe gotten lost.

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#587

Bryan just tweeted this, any thoughts

New Blueprint therapy

Three peptides for thymus rejuvenation, telomere lengthening & epigenetic age slowing/reduction. Therapy showed a 66% all-cause-mortality risk reduction from 6 years of usage.

Intramuscular injection, 10 mg daily for 5 days every 6 months.

Epithalon - 50 mg
TA1 - 25 mg
TB4 - 25 mg

https://twitter.com/bryan_johnson/status/1729246466408055209?s=46&t=zJMJ1xVdRJYEDYz-DHipTw

#588

I’ve dabbled with peptides and I’ve taken all three of these. It’s hard to say whether or not they had any effect.

The research on peptides comes out of Russia and most of it comes from Dr. Vladimir Khavison.

https://khavinson.info/research

The problem with it is that most of it is in Russian and has largely been ignored by Western Medicine.

To add to the difficulty the FDA has recently banned compounding pharmacies from selling a huge list of them. TB1 and TB4 are included on the list.

You can find a link on how to setf administer this therapy on fightaging.org

I seem to remember a person’s results came in and their thymus actually got smaller. But, if you’re motivated and willing to do a deep dive, all of the information is available.

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#589

I tried ordering peptides from India, but they refused to sell them as they cannot be exported.

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#590

This company sells all three peptides.

this one just Epitalon

here is a presentation of peptide usage with some references

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#591

It’s been a while since I was researching peptides but I seem to remember canlabs is a legitimate seller.

They’re in Canada and I’m not sure where things are now since the FDA banned them.

https://canlabresearch.com/

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#592

Hi Folks a short sharing re shock wave therapy for both penis and vagina/clitoris rejuvination.

it works. Its not painful. You can get penis treatment in the morning and have a rock hard erection that evening. For a women its just uncomfortable. The practicioner might offer mild sedation; take it. She will be able to press on a bit more firm to effect the most value. My wife has had 2 treatments and they do help painful sex. If the practicioner is good, can get enough energy into the clitoral area orgasm can return. No one talks about female loss of orgasm… Men get all the air time with ED.

Details as I understand them. I was at the A4M in Orlandor 2023 and took the Gainswave shock wave device training 6am Sat. (OMG). The penis like the heart, has its circulitory system that can “clog up”. If Nitric Oxide bosting (not just Cialis but other Nitric Oxide boosting tactics should be used or in parallel with cialis. I take 2.5mg daily as a health aid for nitric oxide levels in general).

The ultra sound waves generated by a piezo crystal and focusing head do a few things

  • breaks up the junk in the male/female area capularies and gets blood flowing again. 3 -6+ treatments for men. Obese, pre diabetic/diabetic men have real physical challenges in the penis capularies. Female can see benefit in 3 treatments then annual.

  • Angiogenisis via tissue stress and healing energy flowing to that area. More new blood the better the erection.

Dr Gains in Boca FL pioneered this treatment. Many brands of devices today. Find a practioiner on

=== Bryan Johnson at 45???

Of course I have high respect for BJ’s leading efforts even for some what things I’d not want to do. Some I do though.

I do NOT feel Bryans vegetarianism is the most beneficial for living to 100. Too much to get into about my research into the Blue zones eat lots of meat including pork. Pork grows on islands historically.

I wonder why Bryan is getting shockwave in the first place? Low chollesterol low protein diet might be dragging down his penis function? Regardless I wanted to add that this is in my view/education/conferences IS another anti aging treatment. Its not painful or that expensive and is effective as a topping off performance or in the worst as a basic restoritive treatment. Full restoration of near zero function though requires diet, lifestyle (no smoking etc), nutricals (nitric oxide) and 10+ treatments. A few though can be a boost for decent functioning folks.

Practioners; men have it easier. Less experience is needed for good results. For female treatment IMO the practiioner needs to be a women and a few years of experience. My wife found a top practioiner whos main practice is fertility, female restoration as a side value add.

Take care, curt

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#593

At an A4M conf Orlando 2023, a talk on the thymus degrading over time and potential value of rejuvenation… A difficult organ to rejuvenate but if successful probably ALOT of benefit not limited to ones immune system function having more disease resistance etc.

I’d be interested in adding thymus rejuvenation if the protocol can be bought. LOL expense?

tnx to all, curt

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#594

What is the cost? Is it a “one and done” sort of thing, or something to be repeated over specific timeframe?

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#595

Bryan’s Follistatin results. My question is on the duration of benefit?

Screen Shot 2023-11-30 at 11.55.53 AM

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#596

Btw, I know that back to Roy Walford and the birth of human CR / CRON temperature has been a top biomarker of a good longevity phenotype

Does anyone have a good suggestion for device for measuring body temperature upon awaking?

Ideally something that is cloud based and would then connect eg Apple Health (so it in turn can connect to other platforms)

Anyone know what device Bryan is using below?

IMG_6418
IMG_64181179×2556 148 KB

https://twitter.com/bryan_johnson/status/1730233810602660345?s=46&t=zJMJ1xVdRJYEDYz-DHipTw

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#597

Knowing Bryan, its probably an all-night rectal probe (for some symmetry with the erection monitor) :wink:

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#598

Might be one way to stay in an optimal low mTOR, low IGF-1, etc state while not needing to weigh the tradeoff of pushing high protein to gain and keep strength and muscle…

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#599

I think Bryan Johnson will be “in person” at the Longevity Summit (at the Buck Institute, Marin County) next week. If anyone has some burning questions for Bryan (like the above one on what temp. sensor he uses) please post them here and I’ll try to get them answered!

And, a new podcast with Bryan Johnson:

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#600

Why doesn’t he target even lower LDL or apoB despite there being evidence from clinical trials of PCSK9 inhibitors and statins of benefit and safety of lowering from his levels to even lower levels by around 50 points. Why doesn’t he measure apoB?

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#601

Re cold feet/extremities/low waking temp. Get a full thyroid panel. IE from LEF.org, thyroid panel [TSH, T3, T4, free T3, rT3]. i like TSH <1.0, Free T3 needs to be mid range to upper range. As long as rT3 is low. The fix is BHRT for thyroid; desiccated bovine thyroid from your friendly Functional Practitioner. I take NP thyroid. Armor is not on the market anymore. Run from a practitioner who prescribes just T4 / Levothroxin. That is old old school. Many folks with metabolic problems are not good converters of T4 to T3 thus remain hypo-thyroid, which is why a mix of T4/T3 via NP thyroid is much more effective. I’m on 90mg 2x. This is a high dose.

#602

Testosterone (all hormones and Vit D) are derived from cholesterol. The innate immune system is driven from LDL etc. Dropping cholesterol, thus LDL is a loss of youthful hormones and immune function. I like total cholesterol for me around 200+.

The carnivore Drs (low carb conferences) say if your calcium score is low or zero ignore LDL and Apo-b. See my other comments re elevated LDL/ApoB can be an indicator of hypo-thyroidism. We’ve boosted our thyroid function and our LDL/Apo-B has dropped. And a recent accidental bout of tupor (from olive oil dosing) bumped my LDL/Apo-B up. Will report in 8 weeks of mono-saturated fat (olive oil) free will reverse my hypo thyroid panel and elevated LDL/Apo-B. Will report later.

BTW Brad Marshal (??) youtube channel Fire in the bottle has done a fantastic job on tupor driven by fructose and mon-unsaturated fat intake including olive oil, wild animal fats, nuts (IE like hibernating mammals heading into winter gaining fat/low metabolism).

Good luck, curt

PS this thread needs to be broken into new threads???

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#603

Source for this claim?

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