He made his brothers get their arteries checked. Each had advanced heart disease.
1 Like
mccoy
#1191
Iron-deficiency anemia has pros and cons, but if below the lower lab threshold, the consequences can be deleterious, like fatigue, immune deficiency, and other impaired biological mechanisms. The optimum is probably in the lower quartile or quintile of the distribution. No fatigue. Lowered risk of Fe-driven oxidative signals and consequent increased cancer hazard. a typical U-curve hazard model.
I recently exhibited a slight iron-deficiency, the most immediate symptom being excessive fatigue and somnolence. I am taking Iron bysglicinate supplements. Fatigue ceased. I still have to repeat the labs.
1 Like
Kelman
#1192
Is this the best one to take, or any Iron supplement would do?
mccoy
#1193
I took it because the consensus is that chelated Iron, bisglycinate in this case, has some advantages, usually, but not in all cases. The main disadvantage is the higher cost. But not too much. All in all, it seems to be the optimal choice. And absorption is usually improved if taken every other day. This procedure seemingly inhibits the hepcidin anti-absorptive action.
2 Likes
Davin8r
#1194
A heme iron supplement such as Proferrin has major potential advantages over all the others including bisglycinate, chief of which is the convenience of being able to take it with food and likely better absorption and less risk of side effects. It worked extremely well for me.
2 Likes
RapAdmin
#1195
Normalizing blood sugar can halve heart attack risk
New study shows: Prediabetes remission protects the heart and saves lives
For the first time, an international analysis has shown that when people with prediabetes bring their blood glucose back into the normal range through lifestyle changes, their risk of heart attack, heart failure, and premature death is cut in half. These findings could revolutionize prevention and establish a new, measurable target for clinical guidelines. Among others, researchers from University Hospital Tübingen, Helmholtz Munich, and the German Center for Diabetes Research (DZD) took part in the study.
Millions of people in Germany live with elevated blood glucose levels without knowing it. They are considered to have “prediabetes” – an early stage that until now has lacked clearly defined treatment targets. People with prediabetes are usually advised to lose weight, be more physically active, and eat a healthier diet. These lifestyle changes make sense, as they improve fitness, well-being, and several risk factors. However, one crucial question has remained unanswered: Do they also protect the heart in the long term? So far, no lifestyle program for people with prediabetes has been able to clearly demonstrate a sustained reduction in heart attacks, heart failure, or cardiovascular deaths over decades.
https://www.eurekalert.org/news-releases/1109465
Program Outcome study and the DaQing Diabetes Prevention Outcome study.
The Lancet Diabetes & Endocrinology.
DOI: https://doi.org/10.1016/S2213-8587(25)00295-5
Link to publication: https://www.thelancet.com/journals/landia/article/PIIS2213-8587(25)00295-5/fulltext
4 Likes
Yes. Diabetes increases heart disease risk dramatically. At first the two don’t sound correlated, but in fact they are.
1 Like
RapAdmin
#1197
Source: https://x.com/CoachDanGo/status/2000241688204206210?s=20
Of course, this begs the question… where is the research on impact on women’s cardiovascular disease impact?
I guess we just have to assume its equally good of both sexes, and get moving on this “actionable insight”.
1 Like
Virilius
#1198
Reverse causaity at play again? Men who can have sex multiple times a week are fitter and healthier than men who can only do it once a month.
1 Like
RapAdmin
#1199
No, no, no… this is not a paper we want to debunk in any way 
4 Likes
