#69

Is a physician supervising you? I ask because the red flags are popping.

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#70

If so, I hope (s)he has good malpractice insurance after supplying him with unlabeled green-topped hopefully-tirzepatide vials for self-injecting at 5mg Q5days.

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#71

I’m interested in (low end) dosage anecdotes for non-obese, non-T2D folks — ideally for tirzepatide.
Have people tried something like 1mg?
I’m looking to avoid rapid weight loss, RHR increases and HRV decreases. Hoping to find a dose where in particular the latter two side effects are negligible.

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#72

That’s exactly what I’m looking for as well, and I’m also non-obese, non-T2D. Skipped my 2.5 mg dose today, now that I’ve lost 15 pounds too fast (1 month) and have been sick of the elevated heart rate and somewhat disrupted sleep. It took a couple of weeks for those side effects to really kick in (at first I was getting all appetite suppression and no side effects). Planning to restart at 1mg dose some time in the next few days and will report back here with results.

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#73

If you don’t have diabetes and not interested in weight loss, what is your goal?

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#74

See this thread: Intermittent (oral) Rybelsus / Semaglutide use in healthy individuals?

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#75

From where did you obtained the medication?

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#76

Those sides do go away after a while for most.

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#77

That’s what I kept telling myself, but the increase HR was giving me anxiety and I was losing weight too fast anyway despite weight training/protein. Doing careful analysis of my weight training routine, I wasn’t getting anywhere fechar to recommended training volume of 10-20 sets per muscle group per week. Hoping for optimal fat loss and even some muscle gains from lower dose of tirzepatide along with SGLT2i and optimal training volume/protein, but we’ll see if these compounds allow room for anabolism.

I cannot overstate how much I LOVE the freedom from hunger granted by tirzepatide. No longer being a slave to my cravings for delicious high-calorie food (while still being able to enjoy them IF I choose) is so amazing that I just never, ever want to go back. Having a slim abdomen and being well on my way to a 6-pack is just icing on the cake!

6 Likes
#78

I just saw that Eli Lilly will be selling vials of Mounjaro from their web site. Supposedly they are doing this to make up or the lack of supply of the pens and are currently only offering it to those who are not getting reimbursed by insurance. I think your approach is still less expensive.

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#79

My insurance covers it at $25/Month but that’s quite a bit of news.

However, it will be nice to spread the dose out of the higher amounts and help the shortage the best I can.

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#80

Congratulations.
I’m curious, how old are you?
Has your blood pressure improved? How about your lipids? testosterone levels?

I’m just wondering if you may be able to adjust your regimen based upon your lower weight.

#81

My understanding is that if Lilly can make enough to prove there is no shortage, then legally nobody else can make or sell it?

#82

I’m thirty three.

Blood pressure did not improve through weight loss or an improved diet. I’ve tried almost every BP med on the planet before settling on Telmisartan/HCTZ 80/12.5mg which has only improved my blood pressure to 130/80 on avg.

Lipids remained remarkably controlled even when I was morbidly obese, so those didn’t change much. My ApoB has consistently been been 45-70 in three different tests. I do take Ezetimibe chasing that ApoB however.

Testosterone levels when I began supplementing were at 550-600. I began supplementing after I had lost the bulk of the weight and began noticing a decline in my muscle mass, strength and ability on Mounjaro.

Test, Free T and SHBG are sitting at 1131ng/dl, 16ng/dl and SHGB is at 50ng/dl. E2 Sensitive was at 89.7 which is high however, I’ve experienced absolutely no side effects short term and feel fantastic. I do have some excess adipose tissue which can increase E2 but even that is rapidly diminishing after beginning Rapa.

4 Likes
#83

I’ve made good progress with RT while on 5mg of dapa, but I’m still a little nervous about it, wondering if I’d be doing even better without.

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#84

Here’s an article in the pop press saying we’re far too trusting of pharma drugs and also slams ozempic:

" Attkisson points to Ozempic, the latest medical fad, the diabetes drug that’s being sold and marketed as a weight loss medicine.

“Never mind the side effects, including thyroid tumors, pancreatitis, vision changes, low blood sugar, gallbladder issues, kidney failure, and cancer,” she writes. “Maybe it too will be pulled from the market someday.

“But in the meantime, there’s money to be made.”

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#85

Unfortunately, there’s also money to be made in shoddy sensationalistic journalism.

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#86

They fail to mention the medications have been around for decades.

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#87

Until proven otherwise, I think GLP1’s are miracle drugs.

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#88

I ordered from a reseller online.
Tirzepatide works well on me, but the appetite suppression is too strong, I’m going to lower the dosage.

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