Glycocalyx - does it completely absorb damage from glucose spikes UP TO AN EXTENT? Does endocalyx work for regenerating it? Ways to measure its health?

[AlexKChen]

Glycocalyx

The Science and Physiology of the Glycocalyx by Dr. Hans Vink

Glycocalyx Health: Studies That Show How to Restore, Regenerate, and Protect the Glycocalyx

GlycoCheck measurements: PBR as a measure for glycocalyx damage

[AlexKChen]

Measuring the glycocalyx: The GlycoCheck system

[AVS]

Hi Alex!

Did you ever get a GlycoCheck scan? I saw a preventive cardiologist who wants me to buy this test from him. I’d be eager to hear your experience if you care to share.

I don’t see
studies on their website correlating their “Microvascular Health Score” with actual biomarkers of endothelial health.

There’s also the issue of inter- and intra-observer variability and reproducibility.

Still, I’m curious to give it a try. Should I?

Kindly,

Amy

[AlexKChen]

I would love to try it but don’t know where to get it. A4M didn’t have it last year.

[ng0rge]

Very interesting videos and technology. Thanks for posting. Looks like an excellent measure of endothelial health.

[Zanthous]

it’s an interesting area and I did have one person tell me it helped them out for their condition but it’s expensive stuff, and the research, supplements, and everything seems closely tied to one group so it’s hard to see it as something easy to trust. There are 9 pages of studies on their site, with only some being directly relevant to their products and I found one Effect of glycocalyx-targeted therapy on vascular function in older adults: a randomized controlled trial | Journal of Applied Physiology to go through (I don’t want to go through them all) It found the following: Our pilot study suggests that Endocalyx Pro supplementation is feasible in older adults but has no measurable effect on overall glycocalyx thickness and FMD. However, Endocalyx Pro may have select effects on capillary glycocalyx thickness and FMD normalized to shear rate among older adults, but further investigation is warranted.

[Paul]

There is a product with similar claims called Arterisol by Calroy - can buy on Amazon or their website

[Paul]

https://microvascular.com/endocalyx-anti-aging-supplement/

[Paul]

Here is a comparisson of Endocalyx and Arterosil

11-Arterosil-Endocalyx-Factsheet-2301.pdf

[DrG]

Supplement I take for blood vessel support and glycocalyx maintenance.

Cir1 Flow | Support Your Circulatory Health | SRW

[Joseph_Lavelle]

Arterisol is recommended by Dr Twyman a cardiologist who I interviewed this year.

It contains
MonitumRS™ Green Seaweed Extract, Grape Skin And Seed Extract, Green Tea Extract, Grape Pomace Extract, Tomato, Carrot Juice, Bilberry, Broccoli, Green Cabbage, Onion, Garlic, Grapefruit, Asparagus, Papaya, Pineapple, Strawberry, Apple, Apricot, Cherry, Orange, Blackcurrant, Olive Extract, Cucumber

[CTStan]

My doctor measured my glycocalyx function a couple of years ago using an EndoPat machine. It found my endothelial function score to be subnormal. He recommended Arterosil.

I have used Arterosil ever since and made impressive improvements in my endopat score, which is now normal.

However, because I use so many products, I can’t necessarily attribute the results entirely to arterosil.

[ng0rge]

Would be interesting to see a direct comparison between the GlycoCheck and the EndoPAT tests.

Here’s an article looking at different methods that include EndoPAT but not GlycoCheck:

New Noninvasive Methods to Evaluate Microvascular Structure and Function

https://www.ahajournals.org/doi/full/10.1161/HYPERTENSIONAHA.121.17954