What is the “DAV protocol”?
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Flooshy
#43
I think Rapamycin alone is not enough.
As far as I can understand it activates autophagy throughout the body, but the body usually does not seem to prioritize repair/healing of hair because it is not essential for survival. Especially when you have chronic pain or inflammation, the body will probably focus all of its repair on essential organs and tissue.
Also keep in mind that overall health of the body matters. I think when a person’s skin and body has taken signifcant damage from the environment and aging in general, it is almost as if aging accelerates because the dysfunction of the cells cannot be repaired fast enough before new cells go dysfunctional. The probability that the body will repair the hair is extremely low the older you are and in worse shape you are.
I think the highest potential for regrowth/repigmentation is treatments that cause some kind of local hormesis. Microneedling of the scalp and applying of certain substances like Minoxidil show the most powerful changes in hair.
If you want to repigment your hair, I think you must do something to your scalp that triggers the body to repair the hair follicles. I wonder if deep needling penetration in combination with senolytics could work to make this happen but I have no idea.
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Any improvements on the grey hair matter
My main concern with super high doses of omega 3 are heart problems which seem to happen. I was doing pretty high dose for a while but just do 1 fish oil concentrate morning and one at night now.
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What I find interesting from time to time is that individual hairs will change colour part way down the hair shaft. I am mainly seeing a small number of facial hairs turning from white to pigmented. Its a small number, however.
There is one very obvious one in this photo.
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What’s your citrate dose these days?
Its around 20g per day. I should emphasise that I use a number of interventions not only citrate.
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Is enclomiphene to increase testosterone levels without shutting down HPTA?
If so, have you ever tried TRT and if so how do you compare the two?
I’ve just ordered a red light therapy cap. Been using a panel for a little while and enjoyed it so I’ve ordered cap and mask. I think that will improve circulation in the area. I use a scalp massager a few times a week.
I’ve tried many things over the years and I’ve always felt if I ever do anything that reverses gray hair I’ve discovered something that is profoundly rejuvenating unless it’s a very specific topical formula made only to reverse gray hair.
There was the case where they were testing a new anti-lung cancer drug there were consistent numbers of patients getting gray hair reversal. Given the information I’ve learned as of late of senescent cells I wonder if this was some kind of senolytic effect?
The drugs used were Nivolumab, Atezolizumab and Pembrolizumab. I would love to see these used in the Ora Biomedical C. Elegans studies.
