Are these two drugs part of the longevity protocols? Any reason I should switch over from atorvastatin to the Brillo combination drug?
No - they are not part of any standard longevity protocol. Atorvastatin is fine, these other medications just reduce LDL-C / APOB much lower. Many of us are following the work of the lipidologist Thomas Dayspring, and medical doctor Peter Attia, that recommend getting your LDL-C to the 50 to 70 range.
See this thread: Cardiovascular Health - #1436 by adssx
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I think they should be the part of every longevity protocol. You’re not going to improve your lifespan if you die early from a coronary!
It can be paired with Atorvastatin. I take Brillo EZ daily and 5 mg Atorvastatin on Mon-Wed-Fri
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This is what I was asking, thank you so much!
I recently lost a ton of weight and now I’m focused on the longevity protocols. My LDL is at 137.
Prior to my significant weight loss it hover around 90 for many years. My HDL is 103 and my ratio is 1.3.
The LDL has gone up 10 points in three months. I’ve had only several doses of Rapamycin in that time. So I’m not quite sure why it would elevate so much in such a short time. In any event, my MD started me on a atorvastatin to bring it down.
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Rapamycin can elevate your LDL by that much. It raised mine 30-40 pts. Bempedoic Acid and Ezetemibe brought it back down.
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Rapan
#66
Did you check uric acid levels?
Bempedoic acid could increase UA levels which is a concern for me for various reasons.
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Beth
#67
Congratulations on your significant weight loss!!!
I don’t take statins as I am intolerant, so I take repatha instead. But, as you’ve heard from the others above, in order to get my ApoB even lower than a statin/repatha can do alone, I’ve also added on ezetimibe and bempedoic acid.
Thanks! More than 100 lbs, total will be about 120. The GLP1s are a remarkable asset, some real Harry Potter stuff!
I was always healthy but heavy, and not sick enough or fat enough, so after starting with telehealth went rogue with a few underground groups to keep buying them affordable.(Happy to share that info via DM.)
I have wondered if the weight loss (fat breakdown) has caused any of the lipid elevation, but that is an academic musing.
I am now able to focus on getting the lipids under the numbers and increasing the other actions that are necessary!
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I also take Empagliflozin which reduces uric acid. So it hasn’t been a problem.
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