I haven’t been able to find a discussion about this, so I’m posing and asking for comments: https://blueprint.bryanjohnson.com/blogs/news/i-stopped-taking-rapamycin
See this long thread: Bryan Johnson stops rapamycin
and this related thread on one of the key research papers Bryan used to justify his ceasing rapamycin: The Effect of longevity interventions on epigenetic clocks (BioRxiv)