#207

I appreciate the recommendation. I have taken both calcium/magnesium butyrate and also tributyrin before, but I seem to feel them wear off similar to GABAergics. Its not particularly pleasant and since butyrate has a pretty short half life, I experience it often. It does help the GI tract though.

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A drug cocktail of rapamycin, acarbose, and phenylbutyrate enhances resilience to features of early-stage Alzheimer's disease in aging mice
#208

Accidentally edited over my post you replied to but that’s interesting. By GABAergics do you mean it’s similar to a BZD withdrawal or alcohol hangover?

#210

What brand and dose of tributyrin did you take? And, before you deleted your post what exactly did you say it did for you?

#211

Yes, similar to alcohol or BZD withdrawal. I don’t do well with either one historically either, so I am sure it is related to that.

#212

I credit it with drastically improving a severe case of gastritis I’d been dealing with for 3 years. Like severe to the point I had seen multiple gastroenterologists, tons of testing, diets, prescriptions, supplements, etc.

I’ve been taking the brand Healthy Gut for about a year now. It’s on the more expensive side though, and I think there’s cheaper brands out there. I take 500mg in the morning, although some days I’ll take another 500mg in the evening.

Yes, similar to alcohol or BZD withdrawal. I don’t do well with either one historically either, so I am sure it is related to that.

That sucks. I haven’t noticed anything like that, but that would definitely be a deal-breaker for me too.

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#213

@jnorm @Rapa1 @John_Hemming

As discussed I other posts, Blueprint just updated this week and one of the additions seems to be the below butyrate product. What was your experience with the ones that you used? Any thoughts on this one?

  • Revolutionary Digestive Health Supplement: ProButyrate is formulated with Butyric Acid in a sustained-release format, unlike other supplements that use Butyric salts, such as Sodium Butyrate. This palatable butyric acid supplement helps promote a healthy gut

  • Maximum Absorption for Gut Health Support: Butyric acid is a short-chain fatty acid that supports the health of the gastrointestinal tract. Insufficient natural production of this important fatty acid often leads to unpleasant adverse digestive conditions

  • Unrivalled Delivery: Tesseract’s proprietary nano-molecular delivery science results in optimal absorption and bioavailability at micro-doses. A ground-breaking transport and time-release system that enables you to receive the full health benefits from your dietary supplements

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A drug cocktail of rapamycin, acarbose, and phenylbutyrate enhances resilience to features of early-stage Alzheimer's disease in aging mice
#214

I cannot say anything specific about butyrate.

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#215

@Neo I haven’t tried that one. My stomach is very sensitive to anything acidic, which is one reason I went with tributyrin vs butyric acid. Tributyrin shouldn’t release butyric acid until it reaches the intestine, so it should be easier on my stomach.

I’ve been using Healthy Gut brand tributyrin for awhile now but it’s pretty expensive. I may switch to a cheaper brand in the future.

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#216

Im usually pretty leery of proprietary blends, especially when they are nebulous about what makes them special. Most are overpriced and may underdose bioactives. I used the Healus brand when I took it:
https://a.co/d/9W4i6J6

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#217
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#218

Blend them into a smoothie. Or bake them into banana bread or similar. You can also make a chia seed pudding.

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#219

This is an interesting thread to read through. Such a variety of supplements, doses, priorities. A reflection of the uncertainty of the field.

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#220

Yep, and just like flax seeds, they can be an egg replacer in baking

#221

Stay away from multi, it is useless and wreaks havoc on your metabolism. makes your body think you have got all you need and stores all food you eat into fat layers in your belly. Had a girlfriend that gained over 30lbs with no apparent reason, and after a while she realized it was the multi. stopped multi and in 2-3 months her weight returned to normal. Just do most important ones individually i.e. vit c, b vits, vit d and vit k2. btw, vit E and calcium should never be supplemented unless advised by a doc. Magnesium is MUST (new calcium) to be taken daily.
If I were you, I’d also ad UA even at steep prices, seems like a no brainer for 50+ crowd. UA has returned me to my beastly self again. Very good for strength and stamina.

#222

Dude always give a recap of video. save us lazies couple minutes since you have already spent your time watching it. lol

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#223

What does UA stand for ??

#224

I assume Urolithin A. (alternatively Ukraine?)

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#225

stands for Urolithin A …

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#226

which supplement did he stop?

#227

What do people think about Brad Stanfield’s multivitamin? MicroVitamin: A Low-Dose MultiVitamin & Mineral – Dr Brad Stanfield

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