I don’t know.
Given the absence of human studies on inhaled melatonin,
They don’t know either. I supposed the existance of melatonin vapes means that human experimentation is happening. I wonder how stable the molecule is when in a vape, but one would assume it is not doing that much harm as we might already know if it was.
adssx
#368
Yes it’s weird there are zero studies but dozens of websites with thousands of reviews. So millions of people using a product that has never been tested!
1 Like
Nlo
#369
Some of the interest in vapes was generated in response to research about the potential protective effects of melatonin in the lungs against Covid. Sorry, I have not quite mastered uploading information, so bear with me.
Also, an excerpt from a medical news site:
“Because lung melatonin inhibits transcription of these genes that encode proteins for viral entry point cells, application of melatonin directly into the lungs in the form of drops or spray could block the virus. More research is required to prove that this is indeed the case, however, the researchers note.”
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adssx
#370
Protective effect of melatonin against blue light-induced cell damage via the TRPV1–YAP pathway in cultured human epidermal keratinocytes
Furthermore, we found that prolonged blue light irradiation induced DNA damage, which in turn induced YAP–p73 nuclear translocation. These effects were also notably attenuated by melatonin.
Dose–dependent DNA damage protection
3 Likes
They’re available commercially. They work…
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adssx
#372
But how are they better than pills?
From my experience, probably about the same. Sleep did seem to come on a little quicker. They might help people who wake up in the middle of the night who want to quickly get back to sleep fast (all speculation of course)
adssx
#374
Which dose did you take? (of both vapes and pills)
I have taken both. The vapes were poorly constructed, so they didn’t last long before they started to produce a harsh ‘smokey’ vapour. Still had melatonin tablets at the time, so I could compare one day to the next. N=1 and all that, and I only used the vape for a couple of weeks before I had to chuck it.
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