Hi Travis thank you I will try it- I see Life Extension has 1mg. I feel I can benefit from it.

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1mg is a great amount to start out with daily. 5mg is pretty potent but can be useful in times of more acute stress.

It’s good to seek out the root cause of the anxiety but lithium will help.

  1. Berberine does not lower testosterone like Metformin in long-term use for male patients.
  2. Berberine may have liver toxicity (rise ALS/AST when long-term & high-dose), Metformin looks safer.
  3. Berberine may inhibit MAO-B
  4. Berberine may regulate Orexin, but results are complex.
  5. Berberine’s minimum effective dose may be higher than metformin.
  6. Personally, I don’t think Berberine improve sleep
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