We found that mice fed a HF-SHM (high fact-shiitake) diet had ∼86% smaller aortic lesion area than mice in both HF-C (P < 0.01) and MIX-C (P < 0.01) groups and also expressed 31-48% lower vascular cell adhesion molecule-1 levels (P < 0.05) than all other groups. Similarly, HF-PBM- (high fat-portobello) fed mice displayed a 70% reduction in aortic lesion area in the tricuspid valve only (P < 0.05). Both mushroom-fed groups had lower weight gain and fat mass (P < 0.05) than the control groups.
Full article below.
https://www.sciencedirect.com/science/article/pii/S0022316622166897?via%3Dihub
Human equivalent dosage is huge.
According to Wu et al. (12), 10% wt:wt mushroom powder in mice will translate to ∼11 g fresh mushroom/kg body weight, which is ∼750 g mushroom/d (10 servings/d) for a person with an average weight of 65–70 kg.
Assuming the powder is one tenth of fresh mushrooms, that is still 75g (five tablespoons) of powder per day. If the effects scale down linearly, then two tablespoons of powder would produce 40% of the benefit. That is a big if.
The full study has a pic of the lesion area.
LF-C low fat control
HF-C high fat control
HF-PBM high fat portobello
HF-SHM high fat shiitake
MIX-C mixed control
4 Likes
Bicep
#82
Almost 3 inches of rain this week here and high temp and humidity. Mushrooms are blooming like crazy. Embarrassed to say after all the whining I’ve done that most of my cornucopia oysters are blooming. Small so far, but I’m thrilled. This means the mycelium is in there working away. I should get these for years here because these are big logs:
We’ll eat a few fresh, but most will be dried, ground up and frozen for later.
And of course the Golden Oysters are having their 3rd bloom of the year:
9 Likes
Beth
#83
The golden oysters are STUNNING! I’ve never seen anything like it.
2 Likes
Very nice specimens there! Looks like ideal weather conditions for our little fungus friends.
1 Like
Golden oyster - highest source of ergotheioneine.
2 Likes
