5 mg of lithium orotate has 0.19 mg of elemental lithium. It is only 3.8% lithium. Lithium Carbonate is 19% lithium.

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This topic may have already been discussed ad infinitum and I may have missed parts of it in which case I apologize for re-hashing a settled discussion.

I understand your calculation thoroughly, but that’s assuming that there is only 5 mg lithium orotate per capsule. I do notice that the front of the Double Wood label indicates lithium orotate 5 mg, but the label on the back says to me that it is 5 mg elemental lithium (from lithium orotate) which means there’s a lot more than just 5 mg of lithium orotate in each capsule.

ChatGPT, being far from foolproof, I believe agrees with me on this. Here is a ChatGPT summary:

Feature Double Wood KAL
Label Claim 5 mg Lithium (from lithium orotate) 5 mg Lithium (from lithium orotate)
Type of Lithium Stated Likely elemental lithium (but not clear) Explicitly elemental lithium
Approx. Lithium Orotate Content ~130 mg ~130 mg
Approx. Elemental Lithium (absorbable) ~5 mg (assuming label refers to elemental Li) 5 mg (confirmed elemental lithium)
Other Ingredients Hypromellose (capsule), rice flour Vegetable cellulose (capsule), cellulose, organic rice extract blend, silica
Estimated Total Capsule Mass ~140–150 mg ~140–160 mg
Capsule Type Vegan (hypromellose) Vegan (vegetable cellulose)
Public Certificate of Analysis (COA) :x: Not publicly available :x: Not publicly available
Company Transparency Generally reputable; COA may be provided on request Company declined COA to a user (per Reddit)
Primary Use Mood support, neuroprotection, microdosing Same
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I agree on further review that they are listing elemental which is interesting as the Rx Lithium Carbonate is listing the mg of the compound not of lithium. Either way, at 10 mg/day this is still <10% of the minimal therapeutic dose of elemental lithium and certainly nothing to monitor levels of.

Good catch though - but not clinically meaningful in this particular instance.

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image

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Different lots different results

Double wood capsules are in mg of LiOrotate, not elemental Li according to the company. See my post here

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I asked the company a couple days ago, and they said it contains 5mg elemental lithium.

I just replied with a pointer to the Amazon review. Will update with any follow up.

Update:

Still insisting that it’s elemental lithium, even after pointing out the Amazon comment.

The COA from the product web page says 5mg lithium orotate, and the third party test just says ‘lithium’, so seems ambigous.

Just buy something else.

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Wild that even the supplement manufacturer’s customer support is confused about elemental lithium vs lithium orotate.

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If a company cannot answer basic questions about fundamental aspects of their product, but instead engages in a bunch of waffling, it’s time to look for a different product/company.

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If this is true at a minimum change the label to indicate 130 mg Li orotate, 5 mg elemental Li.

Nice discussion of rapamycin (04/11/25) courtesy of Dr. Fraser.

Is RAPAMYCIN the KEY to LONGER LIFE and Better Health? (DrApoE4)

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Thanks - took a while to get the files and then get them formatted. Dr. Barzilai and Dr. Zazala were on that panel, and it was a pleasure to meet them.

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I find the “by design” hypothesis compelling. It looks like the original ideal design is gradually eroded by cumulative damage, leading to a final outcome that may likely deviate from the designer’s intended goal. But what was the initial ideal blueprint if there was one at all? We cannot avoid damage unfortunately…

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I agree also that evolution selects for mean lifespan. This is very obvious when you look at different species. If people want I can give a link to one of my posts about this.

My own conclusion is that the aging and development clocks are the same clock. That is in my poster for BSRA again if people want the link to this again just ask.

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Yes, pls post the link.

This is the link which looks at evolution selecting for mean lifespan.

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There is always hope that if we can’t cure Alzheimer’s, at least little by little, we are reducing the per capita incidence.

Nick (PhD, Oxford; MD, Harvard) is one of my favorite YouTube MDs. His videos are a little shorter than most, and he is not always trying to sell anything or get you to upgrade to “Patreon,” ring that bell, etc.

He is personally interested in Alzheimer’s because he possesses two copies of the APOE4 gene variation.

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What oil is it? (20 chars)

lysophosphotydlcholine, probably spelled wrong. Krill oil is a pretty good source.

I take phosphatydlcholine off and on and he never said whether that would help, or if he did I did’t understand it.

Krill oil--------------------------------------------

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