UPDATE ON NOV 17, 2025
It’s been a while, thanks for the request for an update. My partner, my dog, and I still are taking Rapamycin and all continues to go well.
ME
I seem to recall mentioning a whole slew of things I was taking and doing for health in my previous posts. I have stopped most of them.
I sold the blood restriction bands on eBay. They did tire the muscle early and with less weight. I have little doubt that they work. But they were uncomfortable, the air leaked a little, and I was ultimately uneasy with messing with circulation.
The TECAR therapy seems to have worked on my shoulders, but I put most of my emphasis on my newfound shoulder health on the Crossover Fitness bands that I still use religiously and my ceasing use of Minoxidil, which seems to have been causing fluid buildup that was hampering the healing of my shoulders.
We use the vibration plate just a little. It’s another thing, like the bands, which probably works, but is kind of a pain to use. All that noise and shaking.
For RAPAMYCIN, I have settled into a weekly pattern of 6 pills one week and 3 pills the following week, often with a tablespoon of EVOO (Extra Virgin Olive Oil) or another higher fat meal. I follow this pattern to ensure that my blood levels of rap are essentially zero at least once per two weeks. I’m not convinced that 6 pills weekly allows me to get that low.
I find that Rapa gives me an energy boost between 24-48 hours after taking it, so I take it two days before a weekly high pressure meeting I have. I feel like it helps me have the extra oomph I need to perform well.
I take MELATONIN at about 1-2mg, typically twice a week. It gives me vivid dreams and often makes me sleep in an extra hour or so. I take it before a day off so I can sleep in. If I’m tired and need the sleep, I find the Melatonin doesn’t give me a hangover, but if I’m well-rested the Melatonin will have me yawning throughout the next day. Mostly I take it because of the little bit of research I did, finding it’s good for the Mitochondria and may help with maintaining health.
For other supplements I’m taking a daily D&K2 where the D is 4000 IU. I take Slo-Mag several times a day. I take a high quality Omega 3. Occasionally I take a Cialis.
My hair was helped a lot from the Finasteride and Minoxidil I took. plus the Pumpkin seed oil, but I feel like I nuked my prostate. Even though I’ve stopped all of them I hardly feel orgasms as strong as I once did, even 3 or 4 years ago. I’m in my early 50’s, but I feel like I made a fool’s choice in trying to keep hair and perhaps tanking my ability for arousal and intimacy. I’m keeping an eye on this hoping it is slowly coming back. Low dose Cialis does help, and it turns out going on vacation helps a lot too, so maybe stress also has a lot to do with it.
My blood markers have been fine. I get blood tests once a year in April, so it’s been a while. I insist on getting the ApoB as well as the other standard tests. My lipids are a little higher than they were before rapa, but not so bad that my doc is worried about it.
On the aging algorithms, where you put in all your blood test results and it spits about a biological age, I’ve been consistently several years older on the bio age than actual age. That’s a bummer, but I don’t think it’s rapa’s fault. People say I look like I’m 10-15 years younger than I am, so that’s gotta count for something. Good skin, bright eyes, healthy hair, good energy, etc.
I can’t think of anything else I should add on me, but please do feel free to ask. I did a stupid thing and hurt my left knee, but I’m trying to work through it.
I did make a Rapa buy from China after all the tariffs went into place. I was worried the package would get seized, but it didn’t. I bought Chinese Cialis in that order. It does seem to work less well than USA Cialis. I semi-suspect it’s fake, but then it’ll kind of work. The jury is still out on that.
MY PARTNER
My partner is now in her mid-50’s. Several times she has noticed direct links between her periods happening/not-happening and her rapa use, but I’m sorry to say we’ve both forgotten the details. it’s been two months of no periods now, so perhaps menopause has finally struck. I think it’s fun to think we might get a surprise baby but she rolls her eyes and says there’s no way. Because of travel (we don’t take Rapa on vacation) she hasn’t been consistent with rapa for several months, so that’s another potential tie-in.
OUR DOG
Our dog is 15 and sparky as can be. She gets a big jolt from her weekly rapa of 3 pills. It’s very noticeable that it gives her energy or otherwise makes her feisty. She doesn’t see super well and her back legs don’t seem as flexible as they once were. She slips on wood floors now and didn’t used to. But I can say she’s a happy dog with no major health issues.
Actually, I should say she had some problems with allergies this year. Her feet would itch and she was gnawing on them so much. The vet said she got an infection on her feet so we had to give her a bunch of medicine. We stopped rapa at that time and didn’t reintroduce it until the issues seemed to have been gone.
I know there are concerns that even pulsed rapa can lower an animal’s immune response. Hopefully the rapa didn’t contribute to this.
I need to ask my partner, but I think we’ve restarted rapa since then. Before that Illness our dog was on rapa for probably 3 years straight, except for when we were away.
WRAP UP
I’ve noticed that Bryan Johnson stopped taking rapa. I don’t fully trust the guy, but it did lower my confidence in the drug. I heard maybe Dr. Attia stopped taking it too, not sure why.
I’d be curious to hear if people think that there’s some new game-changing awareness that is making experts give up on the medication. From the little bit I’ve seen and heard I’m not aware of any good reason to stop taking the drug.
It’s weird getting older. As a young man I never thought about illness or -gasp- death. Now I feel it stalking. I sense that I need to keep working out or weakness will come so fast that I may not be able to shake its grasp. It’s not a great feeling. In my arsenal I have: Good work/life balance; Basic supplements like vitamins, minerals, and protein powder; exercise; and Rapa. For now it feels like enough.
My best to everyone,
Higome33
