#331

A good paper on how GHK-Cu rejuvenates the skin and promotes wound healing when applied topically. Also explores the peptide’s effects when injected, finding that, in rodents at least, it has anti-pain, anti-anxiety, and anti-inflammatory properties.

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#332

Interesting effect, new to me so always learning here :smile:

#333

If you browse the reddit peptide forums you’ll see it quite a bit, though it’s still a minority of users and usually fades especially if caught quickly. It’s believed to be due to neurotransmitter modulation. There is a woman on the rapamycin Facebook group who has had a long lasting problem and is now under the care of doctors trying to reverse the brain damage. Quite a few people won’t go near it anymore.

It turned me into an empty feeling castrated robot as if a switch had been flipped. A very strong and disconcerting effect.

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#334

I had it years ago. It’s like an extreme case of burnout.

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#335

It looks NEEL GHSK-Cu tripeptide gel is already sold out and no availability status change expected soon. Their web is alive and kicking though.

#336

Most valuable to know. Do you know if there are cases of this effect happening suddenly and greatly already in the first cycle, without advance warning as you had in your first two cycles?

Reading up, my impression is that severe side effects are very rare with most peptides but it seems BP-157 is an exception. Judging by what you indicate, it’s not very rare.

#337

Was it easy getting rid of?

#338

New city, new job, and the passage of time all helped. But some things, such as my love of music, never returned to the same level as before.

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#339

Was the onset sudden?

#340

Yes, there are a lot of stories of people experiencing this their first time. Usually it reverses after a few days to weeks, but there are also stories of it persisting.

Some dismiss it as purely psychological, but since there’s a known mechanism I don’t think it’s that easy to disregard.

Nasal bromantane is good to have on hand, I think, just in case. It works wonders.

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#341

BP-157 is a strong peptide. Many reports of great results, e.g. with fast healing.

Anecdotal reports of anhedonia being cured, in particular for people addicted to opiates and stimulants. Apparently rewires neurotransmitters.

What scouting the internet also reveals is that paradoxically this rewiring can also cause anhedonia in rare cases. I would not have believed it, if not AgentSmith and Tim had reported it from this very forum.

Nasal bromentane works wonders but I assume there is no guarantee that it will fully roll back anhedonia if this should strike…

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#342

Yes, it and MAOIs like 9-me-bc seem to help stimulant abusers (anecdotally), but I’ve never used those.

I developed neurotransmitter problems in 2021 following back to back destruction of my gut microbiome and a COVID-19 infection, and I suspect that’s related to my reaction.

Most will have a positive experience. It’s just something to be aware of when experimenting with it.

#343

Right, the great majority will have positive experiences.

In my own case, a combination of features may tip over to not using those unopened vials. On an SSRI since 25 years, I may have neurotransmitter issues. BPC is angiosenic and I have a metastatic hopefully still dormant prostate cancer. Not having any major wound I was after the other goodies of BPC including GI, plus curious whether injecting into a longlasting ridiculously minor wound - only ill-effect is preventing me doing one specific resistance exercise - would cure it fast. It probably ain´t worth the risk.

I appreciate your postings.

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#344

Just keeping this valuable and under discussed thread active. We are doing all the above and more peptides AND a round of every organ bio-regulators.

HUGE HUGE benefits from both. Just huge. And a bit expensive. You can’t take it with you. :wink:

The latest high quality peptide info is on youtube. Just search. Favorite channels of trusted latest are:

Hunter Williams, Jay Campbell. Very trusted and latest. This is 1,3,5 yrs ahead of anyone stuck with a License!!! Always trust the weight lifters, vanity folks to ferret out what actually works with actual dose ranges (they are guaranteed to push it too far and report back). LOL gotta love youtube for latest and useful info. Even researchers post on youtube before their papers get accepted… Its a sad state of affairs.

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#345

A lot of peptide vendors out there with every peptide instock; core peptides, polarispeptides, simplepeptides and more.

I store un diluted peptides in the freezer. Once diluted I store in the fridge. Lasts long time. True if left out probably not long at all.

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#346

BIG helps;

Dose calulator; Peptide Calculator – Prime Peptides™

search youtube (Hunter williams channel esp) for: peptide cheat sheet. Jay Campbell has one too.

I agree without the BAC dillution and dose and frequency cheat sheets THEN the needle filling help sheet peptides are very confusing.

Good luck

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#347

By chance, my wife had very good results on her face using NEEL, unlike myself. That’s why I mention it here. For that and because in its origin was the purpose of financing Katcher’s team research on E5. But I am afraid no more.

#348

Started BPC-157 and Epithalon yesterday.
I plan on taking them every day unless I see some negative results in my blood work or experience negative subjective results.

Primary objectives, gut health, telomere lengthening, inflammation, and cognition.
I will not measure the telomere lengthening as I don’t have a baseline and will not spend the money on questionable tests that could be better spent on more peptides.
I will have to take a leap of faith as to telomere lengthening

My take on peptides is similar to my take on rapamycin: If you are young I wouldn’t expect you to have any measurable benefits, with the exception that you are targeting a specific problem such as wound healing, or inflammation.

For old people who are like old cars that need a lot of maintenance to keep going, I think peptides can offer many health span benefits which are also likely to have some lifespan benefits.

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#349

I spent last Sunday night in the ER with a “spontaneous infection” under my kneecap–spontaneous in the sense that nothing seems to have brought it on. It could be a result of aging. Or I could have failed to thoroughly wipe the vial and the skin before an injection. A 12-day prescription for antibiotics is working slowly.

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#350

Did you inject a peptide into your knee joint?