#7

I like it too. He’s become the only one I take seriously.

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#8
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#9

I’ve become a big fan of Physionic.
Thanks for bringing him to our attention.

With respect to the video Attia’s 4 Rules of Longevity (+1 Often Forgotten One), I think we need to consider 3 other things:

  1. Injury repair and prevention (e.g., PEMF, mobility work, …). Maybe part of the first level maintenance, but I think worth including in the discussion. If injures stop us from moving we’ve got trouble. You cover a lot of this on your site.

  2. Systemic inflammation - a lot of the 4 Rules help address this, but don’t necessarily do so directly. Cold thermogenesis provides one option to help.

  3. Microbiome (oral, skin & gut) - our microbiomes affect our health and functional capacity.

I’ve written about this elsewhere on the forum. I think it merits repeating re: these …Rules of Longevity…

Antibiotics saved my life on multiple occasions.

Unfortunately, every course of antibiotics that I have taken since my 20s has worsened or introduced new autoimmune conditions.

Medical science has linked dysbiosis an imbalance within a community of microorganisms) to a range of diseases including allergies, psoriasis, arthritis, Wegener’s, gout, even diabetes.

As example, dysbiosis of specific gut bacteria populations appear to always occur in psoriasis.

This said, to my knowledge, research has not come forward with the imbalance as a cause of psoriasis or any of these diseases|conditions. (Let me know if anyone has more current information).

I’ve seen some reports that the presence of autoimmune issues increases risk of cancer.

The whole system matters and we have an extraordinary amount of microorganisms living on, in, and with us.

I’ve had some success in managing my gut, oral, and skin microbiome, but I certainly have a long way to go to solve the problems.

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#10

Physionic short on Omega 3s.

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#11

People don’t want to take Omega 3 fish oil as it might go rancid. So what?

Rancid fish oil either has no effect or only slightly beneficial according to Physionic.

So, there’s no reason not to take it.

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#12

Check out this thread. I’m more committed to fish oil than ever…plus aspirin

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#13

3.5 hours of Physionic podcasts. Topics are indexed. Lots of opinions on our favorite subjects.

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#14
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#15

Replace your salt with a salt substitute.

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Saúde Cardiovascular
#16

Sorry but could perhaps at least a line be included below those videos that summarises the ‘conclusion’? I realise that sounds lazy, but there are so many videos/Podcasts to listen to, and there is so much info on the forum. Or perhaps could anyone recommend a LLM/AI model that can summarise these videos?

In between maintaining a professional life and social life, doing strength training, cardio, flexibility exercises, reading studies, caring for a family or aging parents, preparing a healthy diet - I sometimes don’t know how people here are still able to get some sleep.

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#17

Switching from table salt to the potassium salts lowers systolic blood pressure and saves a number of lives. They used just (I think) 30% K. Mine is 50%.

I didn’t know I was doing a report, so may have gotten details wrong.

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#18

Thanks. This seems like a no-brainer, but I don’t add salt to anything except a pinch to my 2-serving steelcut oatmeal. I do need to restart measuring my blood pressure. Now that I am using a sauna 4-5 days a week (I sweat a ton in 30 minutes!), I wonder if i need electrolytes …but I’ll wait until I start cramping before adding anything.

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#19
Dementia Prevention - 2024 report of the Lancet standing Commission
#20
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#21

What PEARL concluded was that if you don’t take much Rapamycin not much happens.

I quite like Physionic and have listened to this. He has noticed the absence of enteric coating. He said the researchers “Nerfed the trial”. That is an accurate statement.

Hence his title is pure clickbait.

My own experiment I am doing at the moment is costing me about GBP 300 per week in terms of testing, but is actually getting some clear results (on an n=1 no placebo basis).

The high testing cost will last about 4-5 weeks and then my testing costs will go back to normal.

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#22

Yea, the video itself was a spot on accurate analysis to me. Unfortunately, click bait is the only way to get views on YouTube.

#23

I agree with you about Nicolas using clickbait. I am following him and his YT channel (thinking of becoming an Insider soon) since the begining but lately, IMHO, he is abusing this kind of headlines for a well reputed site like his. In the video on sodium chloride (salt) - Heart attack risk - he admitted “social media rewards engagement and supresses work where people leave early which disincentivizes creators”. Well, we all know its a tight rope to walk for youtubers.

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#24

We will not see much until very long-term studies are done.

Do we really know what to measure in the short term? Such things as CRP are all over the place. Only long-term studies that show absolute survival rates are meaningful. Short-term studies, and yes, 48 weeks is a short-term study unless the participants are followed for many years to come.

FWIW: You can buy enteric-coated capsules from Amazon and put your rapamycin pills in them before taking them with GFJ. This is what I do. I do not use olive oil, fatty meals, etc. because I, from the interpretation of my current reading, want a spike and do not want to increase the AUC.

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#25

Taurine is great for blood pressure, blood sugar, triglycerides and more.

Blood pressure (SBP) reduced by 4 pts on avg.
Blood sugar reduced by 6 pts on avg.
Triglycerides reduced by 18 pts on avg!

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Scientists Discover That Taurine Promotes Anti-Aging
#26
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Glycine is an MTORC1 Activator