Four months on rapamycin reduced my visceral fat. It has not come back in the two years I have been off it.
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Beth
#44
Well fed prior to bed!!! Love that so much!
If you are going to try logging your food, I’ll suggest you check out Cronometer.com. Use the free version. It’s a great tool many nutritionists use. I use it every blue moon to check out my macros and protein intake to make sure I’m on track.
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Just IMO, if your main target is visceral fat reduction, I’d go with a GLP med (semaglutide or tirzepatide, for instance) over rapamycin. There’s much more human data with fat loss from GLP meds. Also, with GLP meds you get reduced LDL cholesterol and increased insulin sensitivity, whereas rapamycin can elevate LDL and reduce insulin sensitivity. We also have data showing GLP meds decrease risk of heart attack, stroke, fatty liver disease, possibly dementia and more, whereas the data for rapamycin is much more speculative and uncertain, with nearly all studies being done either in animals or with daily use in organ transplant patients as opposed to one dose every 7-14 days.
I’m not saying rapamycin is inferior across the board, just that when it comes to fat reduction, we have a LOT more hard data with GLP meds.
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blsm
#46
I’m post menopausal and also feel it’s a bit of a special situation. We generally need a little less energy but still need adequate nutrients.
I took 3 nutrition courses in 2023 after starting rapa because I felt I owed it to myself to improve my eating habits if I wanted to be in this for the long haul so to speak. My goal wasn’t to lose weight necessarily (although it is for most people) but to transition off an animal foods based keto diet which was causing visceral fat gain. I learned how different Macro-nutrients were impacting my blood glucose which was quite enlightening. I also drastically improved my micronutrient intake. I think both of those go a long way toward feeling my best, having the energy to workout and just generally enjoy life more. I was already on rapa for 6 months so it hard to separate out which had the biggest impact but regardless I’m glad to have both in my life. I’m still using the things I learned about myself during the courses and think for me personally finding a way of eating that works for my body is really important at this stage. My body no longer seems to be as forgiving of a poor diet. I’m definitely pleased to be at my high school graduation weight at age 55. I realized when it was all said and done I basically eat according to the American Heart Association guidelines hahaha!
I second the cronometer recommendation. If you’re interested in the micronutrient content of foods be sure to use the NCCDB or USDA entries to get the most accurate data.
The combination of rapa and eating well has been a winner for me.
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This is probably true, but I get the feeling that right now in the USA, given the overwhelming popularity of GLP1s, they are perhaps a lot harder to get. Perhaps my impression is mistaken.
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Jonas
#48
annodately I have 3 people in my cycle who all had reduced visceral fat. Only one is on GLP1s.
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Nlo
#49
Yes, I don’t think I would meet any criteria for a glp1 med. I am all in on green tea and rapa, and will post my subjective results as I progress.
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Very true that access to branded GLPs is limited, but as of now, you can still get them via online telehealth providers and compounding pharmacies. For those who just need to trim some fat rather than lose 100+ pounds, a small dose goes a long way.
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