#151

At the ITP they don’t use a pill gun, isn’t there a slow release form of Rapa that can be mixed with food? Probably prohibitively expensive, but I thought this problem had been solved.

#152

Yes, eRapa is only sold to research labs right now, and is very expensive. And now the company that makes it is targeting some other applications.

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#153

My cat has bad seasonal allergies. I give him a quarter of a Claritin crushed up in his food and it alleviates his symptoms. Stomach acid can eat through wood. Hard to imagine any pill coating survives through the stomach.

#154

My two 15 year old cats have only eaten organic raw meat cat food their whole life. It comes in on a dry ice each month. It is never more than 2 months old because nutrition in frozen food declines after 3 months. When your kitty is 100% dependent on a food you don’t want sub par nutrition. Expensive but monthly cost is less than a dinner out one time with my husband. They are worth it. They are healthy and active with no signs of looking like senior cats. My previous cat passed of cancer at 13 and looked like a little old man at that age. I thought his high end dry cat food was good for him….

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#155

for @JustinDVM

Hello Justin, I am from Czech Republic, here is Rapamycin available for my cats, do You think, it would be possible to get Rapamycine in Poland ? Thanks You very much for response…Josef

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#156

Hi my feline cardiologist scripted rapamune. I live in Australia. I eventually found the tablet form .5 and was told to give him three in enteric coating capsule. They don’t fit. I can’t see how he would swallow it also I can’t fit a triangle tablet into a tube capsule. Do you have any tips. Also does the tablet have it own slow release. I got the proper brand from a normal human compound pharmacy. They ordered them from the manufacturer.
Ps day two and he had very runny poops. Is this normal ? It may be unrelated. He is ten months. His heart seemed to start to fail after having him spaded and they also vaccinated him two days prior to that. They said he would be fine. And he wasn’t unfortunately. I regret - every day, that I allowed the surgery. In the morning he seemed very stressed. Something was telling me not to go through with it but he is a purebred and did need spading as behaviour started to change.

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List of all the Mouse Studies Showing Rapamycin Lifespan Extension
#157

Ps I had to break the tablet in half and then put it in a capsule from a pharmacy that is vege based enteric coated. I did one yesterday and one today. To be honest his breathing rate seems to improved every slight?

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#158

Did they tell you why the pills had to go into an enteric capsule? Human grade rapamycin should already have an enteric coating.

#159

Has anyone had any luck finding rapamycin for their cat in Europe? How did you do it?

#160

From the same source as homo sapiens

#161

But it has to be enteric coated, right? So I will just need a doctor’s prescription but with the right dosage for my cat. I don’t think I can do this without a doctor/vet’s guidance.

#162

See these threads: How to import Rapamycin into the EU Countries? Your Experiences Please

e: How to Get Rapamycin, Where to get a Prescription

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#163

I read many of rapamycin posts at some social media, but Im wondering if the tablets should be crushed to powder or just splitted to fit into delayed release capsule.
Thanks in advance

#164

Paper showing the result of different types of dosing.

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#165

See table 14 and 15 in the paper above

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#166

Hi all we have been prescribed rapamycin for my hcm boy. I’m in the uk.
It’s a big pill. As it’s slow release can it be cut? Any suggestions will be appreciated

#167

In my country vets don’t prescribe rapamycin. I had to prepare the medz by myself.
My boy’s dosage is 1.71mg(0.3mg/kg). Because the cat’s acid in the stomach is mcuh stronger than human stomach, I cut one to 1/3 and put into delaye release empty capsule and cut the other one a little bit, put it into the capsule.
The #2 size(1.8cm length) capsule which I used is not enough for dosage, I had no choice but to make 2 pills.

I think if you get vet’s assistance, you’ll get better way to do it.

#168

Capsules tend to float if you don’t fill them with dense enough stuff. Wouldn’t it be interesting to coat directly the rapamune (for europeans) tablets with the stuff they use on pills ?

#169

There is a new “Cat Health” company…

Company Website:

https://thecathealth.com/

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#170

It’s a shaggy cat story.

I have two feral rescue cats, now approx. 2-3 years old. Getting them to take a rapamycin pill has been extremely difficult.

Because they were feral cats previously traumatized, I am loath to force something down their throats.

Of course, as many cats are, they are incredibly picky about what they eat. Naturally, I tried to disguise the pills using cat “Pill Pockets,” coating them with “Churu” treats, etc. If I ground up the rapamycin and added it to their wet food, they would eat a little and ignore the rest. None of this worked, so I decided to give them a daily cat vitamin with their food as an alternative.

I tried a couple of different brands and found one they would eat with their food. I have been doing this for quite some time. They think the vitamin is a treat and eat it first.

The cat vitamins I bought are consistent with the “Pill Pockets.” etc.

Three weeks ago, I decided to give it another try. I wrapped the Biocon Rapacan tablets with the vitamin pill, which is moist and crumbly. It is tricky to keep it together while wrapping it around the rapamycin pill.

Frankly, I didn’t think this was going to work, and I would be wasting yet another rapamycin pill. But voila! They ate the vitamin-covered rapamycin pills first.

Today, they received their third weekly 1 mg dose. I plan to keep up this routine. (Fingers crossed)

They are still young, active, and in good health, so I haven’t seen any change in their behavior.

I keep a close eye on their stool color and consistency and have seen no change.

Cats are cats, so I cannot say if this will work for others. However, if you do not want to force your cat to take a pill, you can give it a try.

I am posting an Amazon link to the cat vitamin that worked for me.

https://www.amazon.com/Four-Paws-Healthy-Promise-Multivitamin/dp/B085M8197B/ref=sr_1_1?crid=2MM47G6A3SQ5N&dib=eyJ2IjoiMSJ9.sNWxDExLxwWpHwkCMYD-R_lYxIFdocMtRqDIH3ebh99D_2PK9rm9c3vnKvSO5Y9pWBVZZeYdrvyPqmqIeJDtZxPvdYMyU2J4Z7Ez1B_E7X3oYmuGUhx9ghdClTdXG9F4-liYcgkjg3qQOkkgVOCfi253gxwjldTuj4N43JL1W4nE9DQPfqQ6MW11s1nsiGw_HtrzwAby98y7vpW0PBn4sQLGTftNBNQB7cjshrNsTB1gUhxkrBIPVI1HF7CqWbtoPQt__JmPakQfGNCj680KsC75fxAqCf54ukRgU3r3WdA.mFGIObJpZR1ycgp3VgYMK7FKlXHZiP72VjZFDm1W2Ac&dib_tag=se&keywords=Four+Paws+Healthy+Promise+Cat+Multivitamin+Soft+Chews+120+Count&qid=1728858551&sprefix=four+paws+healthy+promise+cat+multivitamin+soft+chews+120+count%2Caps%2C138&sr=8-1

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