Apparently taking low-dose lithium is a senolytic, according to the YouTube video posted by @DeStrider.
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Utilizing the fact that SASP is unique to the senescent cell type, being able to measure specific secretions as a bio-marker may be an excellent indicator for potential and emerging health issues.
Further characterization of senescent cells from diverse cell types that include cells of the brain (neurons, astrocytes, glia, oligodendrocytes) and their secretomes may be helpful in generating senotype-specific (senescent cell subtype-specific) signatures with greater sensitivity and specificity to MCI and related outcomes
Plasma senescence associated secretory proteins: A new link to mild cognitive impairment
Similarly, elevated senescent cells has been observed among excitatory neurons in the brain of subjects with Alzheimer’s disease (AD) showing greater accumulation of neurofibrillary tangles, suggesting that the senescent cells might play a role in the progression of AD.
In the study by Mielke et al., the authors have explored this possibility by analyzing the plasma levels of certain SASP markers to predict risk of mild cognitive impairment (MCI) among older adults
https://www.sciencedirect.com/science/article/pii/S1279770725000855?via%3Dihub
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Bicep
#307
Great picture of artichokes? Which are a poor source of apigenin. Best source is dried parsley.
They mention Rutin which I take and believe in as doing the same thing.
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