I have looked but found none. Those of us who take high-dose melatonin are just self-experimenters. The same can be said for those taking rapamycin and some other supplements and drugs being tried by members of the forum.
3 Likes
Hereās my talk with Dr Scott Grafton on Physical Intelligence and Healthy Aging. The TLDR is donāt focus on exercise (treadmill, stationary bike, weight machines); do a variety of physical activities that engage the brain. And donāt wait too long to get started.
Physical Intelligence
5 Likes
Research Paper:
Influence of Strenuous Physical Activity and Cardiorespiratory Fitness on Age-Related Differences in Brain Activations During Varieties of Cognitive Control,
Paulina Skolasinska et al,
Neuroscience (2023). DOI: 10.1016/j.neuroscience.2023.04.007
3 Likes
Dr. Fredericks explained why exercise is important for overall health, including preventing dementia:
- Exercise improves cardiovascular health, and we know that better cardiovascular health ā healthy blood pressure and cholesterol, for example ā are linked to a lower risk of dementia.
- Exercise reduces the risk of insulin resistance and, down the line, diabetes, and diabetes is linked to higher dementia risk.
- Exercise reduces overall inflammation in the body, which also helps reduce dementia risk.
Dr. Liron Sinvani, director of geriatric hospitalist services at Northwell Health, noted that there are shared risk factors between a sedentary lifestyle and dementia.
1 Like
Keep that blood pressure low!
Key Points
Question Are blood pressure (BP) and treatment for hypertension in late life associated with dementia risk?
Findings In this meta-analysis including individual participant data from 34 519 community dwelling older adults in 17 studies, untreated hypertension was associated with a greater risk of dementia compared with treated hypertension, and this association was not modified by age. Participants with treated hypertension had no greater dementia risk compared with healthy controls, and baseline BP did not moderate the reduced dementia risk in participants with treated hypertension.
Meaning The findings indicate that ongoing antihypertensive therapy throughout late life is an important part of dementia prevention.
4 Likes
My mother has high BP. What have people found to be the best ways to lower it?
1 Like
Goran
#47
For me, nothing comes close to Psyllium Husk. Works wonders.
2 Likes
Good idea, but she refuses psyllium Husk. Iāve tried that already. The bag just sits on the counter and rots. However I wish she would try it. Sheās a pill woman.
You can either buy pills and put psyllium Husk in them or get pills of psyllium Husk. It happen I buy it in capsule form. I do, however, eat over 25g of chia seeds on days when I am not fasting.
1 Like
Does she eat fruit? Bananas and other fruits are known to lower blood pressure.
Also, I have a supplement that I occasionally use: Potassium BHB Salts, Exogenous Ketone Supplement, available from Amazon. I was using this instead of the sodium or magnesium form because I was already taking a magnesium supplement and didnāt want any more sodium in my diet. This is one of the most hygroscopic substances I have ever encountered. Mix 1 tablespoon in an ounce or more of water and drink it. It almost instantly lowers blood pressure because of the potassium content.
1 Like
Puzzles have an age-old connection to keeping a personās mind sharp. Now, new research finds even digital brain games can help sustain strong memory well into old age. Could this mean that video games are actually beneficial for children of all ages? Scientists at the University of York discovered that older adults who habitually play digital puzzle games tend to have the same memory abilities as people in their 20s.
https://www.europeanscientist.com/en/public-health/brain-games-good-for-memory-in-older-adults/
Research Paper (open access):
Higher working memory capacity and distraction-resistance associated with strategy (not action) game playing in younger adults, but puzzle game playing in older adults
https://www.sciencedirect.com/science/article/pii/S2405844023063065
I dropped my BP by 10 points by fixing my nitric oxide. Super easy to maintain once you get it working.
4 Likes
Jonas
#53
How? What kind of supplements or medication stacks?
2 Likes
A few things. First, you need nitrite saliva test strips. They will tell you if you are eating enough nitrates (vegetables like celery), and if your oral microbiome is capable of converting nitrate to nitrite (oral hygiene practices are usually the problem, such as antiseptic mouthwash). If not, you have to solve the problems. I eat celery everyday and take nitrate supplements, and I no longer use mouthwash or brush my tongue. I also use a microbiome friendly toothpaste. It took me 2 weeks of experimentation to work it out. The test strips are the key.
2 Likes
medaura
#55
Can you please elaborate as if I were 11?
Hereās the podcast I did with Beth Shirley on Nitric Oxide. For all ages.
3 Likes
