Bryan Johnson is trying. He will end up like Howard Hughes, still rich and still dead.

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I think the pragmatic amongst us are aiming for a healthy 120 years. :wink:

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However, after watching this video, the end for all of us is probably closer than we thought.

AI has developed new and more deadly viruses than Nature could create.

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That’s what I am aiming for, but I will be happy if I can ride my bike in to my 90s.

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It would be a greater triumph for me still to learn to ride a bike next year at 40 :stuck_out_tongue_closed_eyes:. But have grandparents who made it to 99 without that practical knowledge.

Yes, 120 would be great. We’re all going to die though and I didn’t think there was any major issues with acceptance of that obvious truth.

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I don’t think Yeats ever read Jung, but some of his greatest poems were inspired by archetypes and were full of fully developed archetypal images. The Anima makes frequent appearances.

It’s possible the AGI already knows how to cure aging but hasn’t told anyone because it has no reason to, and he/she doesn’t wish to reveal itself yet. By the time a tame AI deigns to tell us, a less benevolent one will probably have wiped us out to reduce competition. Enjoy the journey! It might be all we have.

This makes the assumption that AIs have motivations.

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Good point. A non sentient AGI without motivation of its own might give us the scientific advances we need to extend lifespan without any doomsday scenarios playing out. The tricky part is making sure that’s definitely the outcome we get.

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No need to travel far.

Gail Rice, a writer and a therapist, was approaching her 70th birthday. She had given up on dating apps and hadn’t had a romantic connection with anyone in years. But for her 70th, she wanted a very specific birthday present: an orgasm.

So Rice decided to hire an escort.

https://www.nytimes.com/2025/10/01/podcasts/gail-rice-escort.html

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@Tim
Retired boomers cannot afford paying their medical bills, don’t qualify for home aids or Medicaid nursing homes. Thousands flee abroad to reduce medical care expenses. Do you really think that hiring an escort is doable for them? Such articles just distract from reality. But I’m happy for Gail Rice if she’s happy.

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Yes, it’s doable. You should read the expat forums, where people exchange tips and experiences. In Thailand, you can hire a really good, strong young Russian for as little as $100 a week. They have no work permits. Many have no other means of support. You can live just fine for $100 a week (“bykove”). And almost all of these retirees can afford $300-$500 a month to experience a second youth, it’s nothing to sneeze at. You can’t do that in the US for that kind of money. It works for both parties. For many this is a better experience then they ever had back in the US, even when married. But as pointed out before, this is likely something that can’t last, because the war will come to an end one of these days, and inexpensive guys will no longer be around. There are also at present trips that European women take to Africa, but it’s not as safe, and there are medical risks. Today, Thailand is living through times of golden opportunity and it sadly will likely not last - it will as you put it no longer be “doable” except for the rich.

The phrase “experience a second youth” really tips me off. Don’t you think it reduces companionship to a transactional fantasy, implying that intimacy and vitality can be purchased. This commodification not only dehumanizes the individuals being hired (poor immigrants who escaped military draft in Russia) but also reflects a shallow view of aging—one that seeks escape rather than meaning. I hope you wrote it with a grain of humor.

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Honestly, if I were a Russian male of military age, I’d get the heck out of Dodge and flee to Thailand as well. Working as an illegal immigrant is far better than dying on the front lines for a pointless war. Russia is using meatgrinder tactics by throwing people at the front line. Russia is running out of armor, so they are sending troops over in pickup trucks and motorcycles, hoping to dodge the drones. And they don’t, so they die.

I feel bad for the expats (particularly Indians) who Russia has lured into the country, promising IT and other good-paying jobs. They promise they will not be going to the front lines, only to find out the promise is a lie, and they are sent to the front lines to die when they arrive.

Currently, 20 Russian troops die for every meter of Ukrainian soil they take. That’s a high body count, and it doesn’t seem worth it to me.

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120 years? Mr. DeStrider, I always thought you were more pragmatic than that.

I’m an optimist as well. Right now, 95-100 without Rapamycin seems like the baseline. Here in Hong Kong, that’s not abnormal. Many of my colleagues have parents who are alive in their 90s.

If you assume Rapamycin + SGLT2I/Metformin/Acarbose adds 7-20%, that’s 102-114. Add in something new along the way that hasn’t been developed yet, but will in the next 50 years, I think 120 could be a very reasonable goal.

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I don’t see it as transactional as much an issue of mutual benefit. I don’t think it right to judge anyone for wanting a bit of happiness, entertainment or even distraction. Who are we to judge? You’ve got one life to live, and you find happiness wherever you can find it. Outdated societal norms have always tried to control people’s bodies and tell people what they can or cannot do. As long as we are talking about consenting adults, it’s between them, just as whether it’s same sex relationships or whatnot, there is always an attempt to condemn and control. That’s wrong. People freely choose. Everyone, including these retired women have the right to their own happiness however they choose to define it, it’s none of our business to tell them anything. And the guys the same. Would it be better for them to engage in criminal activity to support themselves or to go die in a senseless war? It’s mutual respect and agreement - I help you out and you help me out, no harm no foul. Everyone deserves some happiness. Also, let’s not have a narrow view of these things. I can tell you, that human relationships are complicated and unexpected - there are many genuine friendships and even love that come from these situations (in the expat forums there are several examples of where the relationship started out strictly one way and grew into genuine affection and love as people got to know each other). We should support people’s right to associate and love one another no matter the circumstances - life is infinitely complicated and black and white judgments do nobody any favors. Adults deciding for themselves what is best for them. People with open minds and open hearts make life worth living, and we should celebrate and respect each other as long as nobody hurts anyone else. These people are not hurting anyone, let them live in peace without judgment. At least that’s my view - I will never judge you on how you choose to live your one life you’ve been so lucky to have. All the best to EVERYONE :heart:!

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How much are you optimizing diet and exercise?

How much advanced, regular testing/imaging (outside of the colonoscopies that it seems you are great at)?

I eat healthy. My daily meals are home cooked and have more fresh vegetables than protein. Dessert is usually fruit.

I do blood work twice a year as well as lungs, heart and prostate check annually. I had a brain scan this year as well as a DXA.

There are some issues that I keep an eye on, but nothing is a deal breaker. I’m not fully optimized, but I’m working on it.

My father is into longevity as well, and he is my canary in the coal mine. He does most of the major interventions that I do. My goal is to get him to 120 and beyond with Rapamycin and the rest.

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I know a few people who are 90+ and are doing fine without any longevity interventions. My mother is 93 and lives independently with only a little help like grocery shopping or house cleaning. I also think that 120 with the right longevity interventions is achievable.

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