Congrats on the results! My bet it that it’s the vitamin K2 that caused it. I have never seen any indications or evidence of taurine being able to improve bone density and can’t think of a mechanisms by which it would be able to do so. In contrast, there is evidence of K2 increasing bone density.
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Agetron
#81
Hello Olafur -
My research and results say different.
Granted it’s rats… Effects of taurine supplementation on bone mineral density in ovariectomized rats fed calcium deficient diet - PMC
Yes, according to research, taurine can potentially improve bone density by stimulating bone formation and inhibiting bone resorption, suggesting it could be beneficial for maintaining bone health, particularly in conditions like osteoporosis; however, more research is needed to fully understand its mechanisms and optimal dosage for bone health.
Key points about taurine and bone density:
Taurine promotes the activity of osteoblasts, the cells responsible for building new bone tissue.
Studies indicate taurine may help inhibit the activity of osteoclasts, cells that break down bone tissue.
Taurine is thought to influence bone metabolism by impacting the differentiation and function of osteoblasts through various signaling pathways.
Taurine supplementation may be beneficial for individuals at risk of osteoporosis or experiencing bone loss.
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It may theoretically have potential to increase BMD, but in this study you linked to, taurine did not increase BDM at all. From the results section:
“In the control diet, spine BMD was significantly lower in OVX rats than in SHAM rats (0.095 ± 0.01 and 0.084 ± 0.08 g/cm2, respectively p<0.05), and in the taurine group, spine BMD was significantly lower in OVX rats than in SHAM rats. They were not significantly different from each other within SHAM and OVX groups by taurine supplementation (Table 7).”
“Mean femur BMD and BMC in the taurine diet group did not differ significantly from that in the control diet group in OVX rats fed 50% of recommended Ca diet. Also femur BMD/weight and BMC/weight of taurine group was not significantly higher than that of control group in OVX rats. (Table 8).”
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lolex
#83
Thankyou so much for this post !
I have been taking Vitamin D and Concentrated K (the best K2 etc supplement) for 8 years. I thought I was in the clear. But I had a bone density test recently and was devastated to learn I have ostopoenia.
I follow several health/supplement streams, but had never heard any mention of Taurine re bone density which I was aware of. I just thought it was a booster in Red Bull.
Thankyou ! I started my taurine this week…
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Agetron
#84
Hey Marko,
Like you I was shocked to learn I had the start of osteopenia - what? I as told it is old age and I might slow the progression, but can’t go back or stop it.
Radiologist told me take K2 vitamin and a Calcium supplement… she said maybe you don’t move as fast into osteoporosi. When I had a reversal back to normal - same radiologist said she was surprised and double checked what I was doing. I think she was going to start taking it… hahaha.
Two years ago 2022 osteopenia
Current 2024 normal
Taurine a nice heaping teaspoon full with 1/2 a teaspoon of creatine in the morning coffee. Give it a try - only took 1 year use for me to have results. Would like to see a few more N=1 with same benefits.
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lolex
#85
Boron is also said to help with bone strength - “The absence of studies showing harm in conjunction with the substantial number of articles showing benefits support the consideration of boron supplementation of 3 mg/d for any individual who is consuming a diet low in fruits and vegetables or who is at risk for or has osteopenia; osteoporosis; OA; or breast, prostate, or lung cancer.”
I took it for a while.
It’s a long review of all the benefits of Boron micronutrients. Many benefits covering many conditions.
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Agetron
#86
Wow! Thank you back for this post!
Long article - but only because boron does so much… nice!
I think I need to add Boron to MY SUPPLEMENTS for contiued bone density improvement, testosterone benefits and reduction in inflammation to name a few. And yes I am guilty of consuming a diet low in fruits and vegetables. Steak and potatoes guy with a bit of salad and veggie now and then.
Let’s give a try for a year and measure the benefits.
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Agetron
#87
Thanks Marco… why not continue the good bone density. My boron from amazon arrived and I have been using it daily for a few days now.
I was watching the latest Physionic vid on Creatine and it appears that Creatine also strengthens bones!
Research has shown that taking creatine can lead to an increase in bone mineral content , which is important for bone health and strength. One of the ways it provides this benefit is by increasing calcium absorption and protein synthesis. Both of these are important for strong bones.
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Agetron
#89
Preventing osteopenia… which leads to osteoporosi is a good thing.
Pretty sure the taurine helped take me from osteopenia to normal. 
Creatine been on it about 4-5 months… it is having a positive filling out effect. Gained 8 pounds… looks good…probably a lot of water in cells of muscles.
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@Agetron, that’s good news, thanks for sharing. Here’s another case study, this time in a woman, that supports the reversal of osteopenia with rapamycin.
a 52-year-old Caucasian female patient with osteopenia who experienced an unexpected 15.9% increase in lumbar spine BMD within two years after enrolling in a clinical trial involving low-dose rapamycin
Full text: Unexpected Increase in Bone Mineral Density With Rapamycin and Low-Dose Naltrexone: A Case Report of a 52-Year-Old Woman With Osteopenia | Cureus
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Agetron
#91
Nice!
My change was -1.2 lumber to -.8 Lumbar. -1 pelvis to -.9 Went from Osteopenia to Normal in both areas. Overall unexpected and very impressive.
I feel the Taurine had a real benefit in my Rapamycin/Taurine combination.
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Make sure you keep an eye on your free T levels. Boron can suppress SHBG. I started supplementing with 6mg / day on boron a few months ago after getting a testosterone panel. I haven’t done the post-treatment panel yet, so I can’t say for sure yet, but it’s something to keep an eye on.
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Agetron
#93
Just looked it up…
Boron supplements can lower levels of sex hormones binding globulin (SHBG) . SHBG is a protein that carries the sex hormones through the blood. By lowering SHBG levels, boron increases the amount of free testosterone and estrogen in the body.
Very nice!!
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Tim
#94
Hyped as a fat-burning peptide, which is doubtful, AOD-9064 seems to be more effective in treating osteoarthritis. A recent x-ray showed that I have bone-on-bone osteo in my knee, but it doesn’t hurt, even when I run. To maintain or improve my knee health, I do daily injections of AOD-9064 with a short 1/4" needle at various points around the kneecap, hoping that it penetrates into the subpattelar cavity.
The best results are obtained with an intra-articular injection of AOD and hyaluronic acid, which are delivered directly with an 1.5-inch needle. I haven’t found a place near me that provides such a treatment, so when the time comes I may attempt the injection myself. Seems risky, but we’re all risk-takers here.
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I had one hormone panel done in August and another just over six months later in February. In the intervening period, I was taking 6mg boron per day.
August February
Total T: 975 ng/dL [264-916] 963 ng/dL [264-916]
SHBG: 77.1 nmol/L [16.5-55.9] 52.3 nmol/L [16.5-55.9]
Free T: 146 pg/mL [52-280] 18.7 pg/mL [6.8-21.5]
The Free T test was obviously done differently, with the reference range changing by a factor of about 10. But the reference ranges for Total T and SHBG stayed the same between the tests.
I think one can reject the null hypothesis that SHBG was unchanged between August and February. The impact on Free T also seems clear.
This supports the theory that boron supplementation can suppress SHBG.
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There is a mouse study on PubMed comparing bone density for three forms of strontium.
Agnieszka Tomczyk-Warunek et al.,. “Influence of Various Strontium Formulations (Ranelate, Citrate, and Chloride) on Bone Mineral Density, Morphology, and Microarchitecture: A Comparative Study in an Ovariectomized Female Mouse Model of Osteoporosis,” Int. J. Mol Sci. 2024 Apr 6:25(7):4075.
Figure 3 shows that strontium chloride increased bone density more than strontium ranelate or strontium citrate. Strontium citrate increased bone density the least. )-:
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Great results.
I am using boron every day.
Need to check Testosterone.
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I read about this yesterday!
I have osteoarthritis in my left little finger and it has accelerated over the past 8 months. had an x-ray this past friday and the report thatrest of my hand is OK, just 2 joints in the littel finger.
Your experience with AOD is interesting and I’m thinking I might try to do an intra-articular injection myself. I have AOD in stock as well as ULWMW hyaluronic acid 
Here is the study I read.
Effect of Intra-articular Injection of AOD9604 with or without Hyaluronic Acid in Rabbit Osteoarthritis Model
More info on peptides that may benefit the joints.
Peptides for Targeting Chondrogenic Induction and Cartilage Regeneration in Osteoarthritis
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Tim
#99
If you can’t bear the pain of an intra-articular, you might try injecting your finger around rather than in the joints. It may hurt anyway. You could also take daily HA capsules to complement the injections.
I gave up on doing an intra-articular because it requires a series of eight or nine shots. I could probably do one, but not eight. Injecting around the knee’s perimeter is painless and seems to be working.
https://www.amazon.com/gp/product/B07GBMPZKD/ref=ox_sc_saved_image_2?smid=AQZ1IMSKWJKJS&th=1
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