José
#13
Available as supplements online at many sites.
Been around since 2018, yes 2018
Review
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That page isn’t selling it, it’s just a writeup of some information. You can purchase it on a number of different research chemical websites, but we don’t have enough human data for that to be advisable.
I’d rather put the money I’d take spending on getting this towards a new lifespan study and get more data. This is what I am organizing here. Hopefully the fundraiser is up soon.
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There are places it can be bought. However, as it stands we don’t know much about it. It might be useful and it might not.
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José
#16
As I have posted countless times…
“If you wait until you are ready, it is almost certainly too late.”
~ Seth Godin
“I am not the waiting type.”
~Joseph
You can wait.
I purposely did not post a site selling this compound.
It was a article by “Marion Tible PhD a researcher in cellular biology and physiopathology. Formerly a researcher in thematics varying from cardiology to neurodegenerative diseases.”
It is not difficult to locate and purchase this compound
Simple search
FWIW…
2004 patent…
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If you do use it please give as much information as you can on your experience. I am interested to hear it from the perspective of someone interested in longevity.
José
#18
Also discussed on this thread…
…
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katiii
#19
I’d love to see lifespan studies on this component too! Any chance this could be done via crowdfunding? A +260% median lifespan extension might be highly unlikely in mammals, but it’s really intriguing. Running a small study could be worthwhile, and the worm bot might be a great place to start.
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So are you willing to put up some cash towards the wormbot. It costs USD400 and USD200 have been promised so far?
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katiii
#21
Yes 
I think we need one more person and then we’re ready to go!
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F it…. I ordered a gram from UmbrellaLabs. Added a gram of ibutamoren to my order and with 10% off from a discount code I found online, another 10% off from orders over $100, and 5% off from paying with a US bank, the total came to $100.58 for them both. Pretty good!
What made me pull the trigger is the batch by batch certificate of analysis. They use mass spectrometry too from an independent U.S. based lab. For details:
I’ll tell you if it feels like anything at all. It’s a gram. Won’t kill me. I’m curious if it does anything. And I’m pretty inured to placebo.
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I’m interested in all user reports at this point due to how little is known on human effects.
Excellent that’s 3 people! I’m just waiting to hear back from Ora about doing the crowdfunding on their website. Might have to wait until the beginning of next month but we will see. As long as people are willing to wait a bit longer then it is ok.
4th person here - happy to contribute US$ 100. I guess that means we’re there? All I need is details on how to make payment to Ora Biomedical…
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Amazing, thank you for supporting this.
I’m going to email Ora again and inform them that we have 4 people willing to contribute $100US each. Maybe they can expedite this before the official launch of the new fundraiser capabilities on their website.
I will report back when I hear more.
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@medaura I’m curious - how will you decide things like how to take it, dosage, frequency etc? Wild-ass-guesses? Or do you have a protocol for how to approach it? Kudos for having a go!!
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I did a Deep Research prompt on ChatGPT to learn more about the substance and it estimated that 5mg a day would possibly be a reasonable dose for humans. Obviously this is not medical advice, or something I can recommend humans do.
If I were to use this substance I would use it in the evening. I suspect combining it with a high dose of melatonin would produce even more favorable effects.
I am incredibly curious on hearing anecdotal reports from longevity enthusiasts who are willing to use the substance.
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katiii
#29
I’m looking forward to seeing this move forward. Thank you so much for posting about it here, I would have missed it otherwise. No matter what comes out of it, it seems like a very interesting substance and it’s a shame we don’t have better data yet.
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I am not quite sure why that would be. I don’t intend trying this although I do intend continuing with my over 1,000mg of melatonin a night.
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Supposedly IPAM does not bind melatonin receptors, so it doesn’t clash. IPAM can be stimulating to some, melatonin will balance that. IPAM has a longer halflife than melatonin.
High dose of melatonin helps you sleep in case IPAM interrupts sleep for some, and you get the benefits of IPAM during the night when you’re not in need of ROS.
Just a theory.
My main reason to take melatonin is to protect mtDNA. IPAM may also reduce harm to mtDNA. Melatonin probably helps with the autonomous nervous system, however.
