Hi everybody,
A small post to ask you what do you think about the drug class of the aldosterone antagonists/blockers, also known as mineralocorticoid receptors antagonists/blockers for longevity, or just in general.
This class of medication works by blocking the effect of the adrenal gland hormone aldosterone wich main effect is on the kidney : it increases the reabsorption of sodium, and make you pee potassium.
The mineralocorticoid receptors are also present on the heart, blood vessels, and liver. It seems like blocking this hormone helps wich kidney disease, heart failure and improves insulin sensitivity.
The main side effect is hyperkalemia, wich mostly happens if your potassium is high to begin with and if your kidneys are sick.
The three main drugs of this family is spironolactone (blocks the aldosterone receptors, but also androgen receptors and progesterone receptors), eplerenone (blocks the aldosterone receptors, not as much nevertheless, and almost no AR, or PR antagonism), and finerenone, the best of the three, ultra sensitive and powerful on the MR, and no other antagonism.
