Antibiotics damage the colonic mucus barrier in a microbiota-independent manner

Joseph_Lavelle · 2024-09-12T00:58:25.628Z

https://www.science.org/doi/10.1126/sciadv.adp4119

“Antibiotic use is a risk factor for development of inflammatory bowel diseases (IBDs). IBDs are characterized by a damaged mucus layer, which does not separate the intestinal epithelium from the microbiota…. Thus, antibiotic use might predispose to intestinal inflammation by impeding mucus production.”

KarlT · 2024-09-12T03:21:32.489Z

Interesting article. I wish they used different antibiotics. Neomycin and Vancomycin are poor choices to test for orally administered antibiotics. Erythromycin class would have been better.

LaraPo · 2024-09-17T00:24:29.765Z

CNN – 16 Sep 24

Nearly 40 million people could die from antibiotic-resistant superbug...

The number of lives lost around the world due to infections that are resistant to the medications intended to treat them could increase nearly 70% by 2050, a new study projects, further showing the burden of an ongoing superbug crisis.