I was listening to an influencer/body builder. He started using mirabegron. He said in addition to helping him urinate less at night, it seemed to help him lose more weight and tighten his skin. Anyone taking mirabegron experience these benefits?
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Some interesting studies on this:
Seems promising for pleiotropic effects. The increase in adiponectin is particularly interesting to me as mine is on the low side, likely due to low body fat levels. Perhaps if I can activate more browning with this drug it might counteract the effects of low body fat.
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Meta analysis on BAT activity:
Through our meta-analysis of 6 papers, we found that mirabegron has the potential to increase human BAT activity, REE, NEFA content, body temperature, HR, blood pressure, and blood insulin content. These effects may lead to reductions in blood glucose levels in obese/overweight and diabetic patients. Additionally, the activation of BAT by mirabegron could represent a novel approach for treating obesity, diabetes, and cardiovascular disease.
Nebivolol (beta blocker) is apparently also a beta 3 agonist.
Fantastic info. Thanks for sharing it!
