Astaxanthin: A Potential Treatment in Disease and Aging, Lifespan Increase

[Michele_Watson]

I am always so impressed by the deep knowledge here. Being academic and interested in the scientific side I learn so much from this site. Although I dont yet use rapamycin I am still very interested in other supplements that have efficacy. Thank you everyone!

[scta123]

There are also specific “tan in a bottle” supplements marketed towards skin color usually containing astaxanthin.

This is one of many.

FIRUNA Tanning Gummies, Natural Tanning Supplement with Astaxanthin, Lycopene...

[jeanbaptiste]

It’s just carotenodermia!

My hand (orange one) vs my mother’s hand

[DeStrider]

@jeanbaptiste Is the color difference all from the Astaxanthin? Or do you get a lot of sun exposure as well?

[jeanbaptiste]

I’m also taking melanotan 2 at 1mg a day, but the orange-yellow color is definitely from carotenoids supplementation. No sun exposure in France, it’s winter and very cloudy

I take 12mg astaxanthine and lutein/zeaxanthin/lycopen, 35mg/5mg/15mg if I remember well. More like an experiment to increase serum albumin level. It seems to work I was 52g/L last time I checked!

[Curious]

keep us updated about your Album, Please.

Lutein/zeaxanthin/lycopen is an interesting combination, especially lutein/zeaxanthin for eye health and brain health. Now in Jan 2025, it is higher up on my list of useful compunds than it was a few years ago.

[jeanbaptiste]

I’m disappointed, I did a small check-up this morning and albumin is back to baseline. Last time I might just be dehydrated

[Beth]

@Curious and @jeanbaptiste

I had not realized lycopene was potentially good for eye health until you mentioned this.

I had wondered why they put that in the blueprint supplement I take

Based on another thread and video shared, I have added Meso zeaxanthin into my mix.

I have a friend losing his vision due to macular degeneration, so I’m all about taking eye vitamins this year.

[DeStrider]

The head researcher of Astaxanthin that provided the Astaxanthin for the ITP.

Astaxanthin Expert: Mistakes, Side Effects, Doses, Timing, Brands, Storage - with Dave AX3 Life

[jeanbaptiste]

Super interesting. Thanks for sharing. Gonna eat salmon this morning, it has a been a long time I didn’t eat some.

[Viracocha]

Thanks for the interview! I think I have found the study about plaque formation. I am going to experiment with quadrupling my dose!

https://onlinelibrary.wiley.com/doi/full/10.1155/2017/4625932

[jeanbaptiste]

What’s said is done lol
Farmed salmon, coocked tomatoes, 0% yogurt with chives and salt, and fruits bowl with kiwis, banana, blueberries and cocoa nibs.
And of course the astaxanthin supplement NatAxtin

I don’t for you but in France the increase is fresh fish price is unreal.

[EverVital]

Good video, that AX3 guy knows his astaxanthin.

Key information on dosing is humans are much more efficient at absorbing asta than mice, so the ITP dose that we originally converted as more than 1,500+ mg, is equivalent to about 12 to 24 mg of the good astaxanthin. Multiply that by 3 if you’re using Now or Bulk Supplements brands.

Dosing: 12-24mg of AX3, or 36-72mg of Now or Bulk Supplements astaxanthin provides equivalent serum concentration in humans as the ITP dose in mice.

[Joseph_Lavelle]

@EverVital

Multiply that by 3 if you’re using Now or Bulk Supplements brands.

I assume this is the claim by the competitor. Was any evidence offered?

[JuanDaw]

DeStrider’s post says “Summary at 29:50”.

Here’s a quote.

We do not have evidence to show, that Astaxanthin has likely an anti-wrinkle effect. So it has a benefit in terms of skin moisture and elasticity, but not the skin wrinkling.

29:29

Vid is 31:32 long. I only viewed the summary. Physionic provides vid chapter/portion titles.

0:00 – Introduction
0:52 –Topics Covered
2:05 – Mechanisms of Action
15:57 – Meta-Analysis Bias Assessment
21:27– Astaxanthin on Skin Moisture [and How to Read the Data]
26:54 – Astaxanthin on Skin Elasticity
28:02 – Astaxanthin on Skin Wrinkles
29:45 – Mid-Point Conclusion/Take Aways

[JuanDaw]

Brand	Claimed Amount	Tested Amount	Price
Bulk Supplements	12 mg	13 mg	$28.87 per 180 of 12 mg
Doublewood	12 mg	14 mg	$29.95 per 120 of 12 mg
Health Thru Nutrition	12 mg	15 mg	$22.45 per 60 of 12 mg
Horbaach	12 mg	13 mg	$29.95 per 120 of 12 mg
Micro Ingredients	12 mg	15 mg	$26.96 per 120 of 12 mg
Now			$39.99 per 60 of 12 mg

Tested mg contents from the link at post 311 by scta123

[EverVital]

@Joseph_Lavelle

Was any evidence offered?

He mentioned a study his team performed that had the same group of people take AX3 and then later, another brand. They measured peak concentration and AUC over 24 hours. He claims both measures showed AX3 was on average 3x higher.

Bulk Supplements is way cheaper though. You get 3x the amount for less than half the price of AX3. That’s what I use, 120mg per day, 4 days per week (away from weekly rapamycin dose).

[LukeMV]

Fantastic video. Long, but it’s a full synopsis of astaxanthin.

Been using the bioavailable form he talked about ever since the ITP results, but I take 12mg because it would be pretty cost prohibitive to take more on a daily basis.

I really think the boost in the Fox-O pathway could be responsible for the longevity.

[DeStrider]

The best dose is…

Astaxanthin BEST Dose Investigation (108 mg Experiment Included!)

[LukeMV]

1-2 pills of the AX3 Astaxanthin per day (12-24mg), but even 8 pills per day showed better lipids.