In case this hadn’t been posted here, this is worth reading for anyone following Bryan Johnson (Blueprint”). It appears the article is based on interviews with past employees and email records. If you are trusting this man with your health, it should give you pause.
Highlights (copied from article):
- Of the roughly 1,700 participants in the study (a study of the supplements and meals called “The Blueprint Stack.” ), about 60 percent experienced at least one side effect, according to internal emails, spreadsheets and other documents. Blood tests revealed that participants saw their testosterone levels drop and became prediabetic after following Mr. Johnson’s diet plan. It’s unclear how severe the side effects were.
- Last summer, Dr. Zolman (Mr. Johnson’s longtime longevity doctor), left Blueprint after raising concerns about the study’s results, people familiar with his departure said. He had signed a nondisclosure agreement, but Mr. Johnson wanted him to sign another one in return for a month of severance, they said. Dr. Zolman declined because of the stringent terms.
- Mr. Johnson did not publish the study’s results by the summer of 2024, as he had told customers he would. In January, he [released some data for about 300 participants, showing positive results. The supplements continue to be sold.
- In an email to The Times, Mr. Johnson said metrics about Blueprint’s supplements “transitioned to or stayed in the normal range throughout the entirety of the study.” He added that Dr. Zolman had resigned “to seek professional help for his serious mental health concerns,” without providing evidence. Dr. Zolman did not leave for those reasons, people with knowledge of his departure said.
- In the Netflix documentary, which was largely filmed in 2023, Mr. Johnson said his biological age had reversed 5.1 years. But the results of a range of internal studies of his health between January 2022 and February 2024 showed it had increased by as much as 10 years, according to charts of the blood test results. It’s unclear what his current tests show.
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AnUser
#2
There is a discussion about it starting from here:
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In the end the priority really should be the science.
I wasn’t aware Oliver Zolman had walked.
people with knowledge of his departure said.
This is press speak for someone subject to an NDA. Normally “friends of …” which includes as a category the person themself.
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Beth
#4
Hmmm, I don’t follow his diet plan, but I am curious what about it would make people prediabetic ? I’ve never been interested in many of his food products because they contain too much saturated fat for me. I would not have been surprised to see a rise in cholesterol for some, but I am curious about the diabetic aspect.
I do take his essential and softgel supplements because I get a ton of things I’d be buying separately in only 3 pills. I’ve gone on the assumption that someone out there is testing his pills to see if what is on the label is actually in them because if they found discrepancies, their YouTube would go viral … someone correct me if you don’t agree.
It was concerning to learn Zolman left
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The guy was always nuts. I wouldn’t buy a single thing he sells because I know when I see the crazed look of a tech bro high on his own supply whose sense of reality is whatever gets him validation at the moment.
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AnUser
#6
This is the same type of comment Michael Lustgarten gets on his facebook page.
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To be fair, @ConquerAging is a little nuts. In a good way.
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Yes… but ML is a little nuts in quite another way. You can probably hunt down yt videos where he’s all in on aliens having produced ancient artifacts here on earth and various other, how should I put it, diplomatically, “exotic” ideas. In the health space he’s pretty grounded, but in outer space he’s off his rocker looking for aliens
…
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Alpha
#9
The last bit (emphasis mine) in the following sentence from the NY Times article raises questions …
The 47-year-old former Mormon missionary has become known for experimenting on his own body to defy aging, captivating the media and his nearly four million social media followers by receiving the blood plasma of his then-17-year-old son and repeatedly shocking his penis to increase his erections.
Apparently men and doctors to men have done this for a while:
WHAT IS EXTRACORPOREAL SHOCKWAVE THERAPY?
The popularity of a nontraditional treatment of ED is growing: Low-intensity shockwave therapy for ED. Gone are the days of medication therapy as the only treatment option. Also known as Gainswave therapy, Low-intensity shock wave treatment is becoming popular as a safe, noninvasive, drug-free treatment option for ED.
It uses low-intensity shock waves applied to different areas of the penis and surrounding areas to breakdown plaque in the blood vessels and repair them to improve blood flow. It is non-invasive (no cuts), requires no anesthesia, no downtime and causes minimal discomfort.
Key question for Bryan Johnson
47-years old. Biological age around 42-years. If all true or even remotely true, why would he need to shock himself to increase his erections (apparently every day)?
I remember my id 40s as a ___________________________ pretty wonderful time and very much in the prime of capacity.
Seems like a job for PEMF
All the things reported about what EXTRACORPOREAL SHOCKWAVE THERAPY does, seems very aligned with what PEMF (Pulsed Electo Magnetic Frequency) therapy does.
Easy to do. I’ve got a PEMF device in the drawer next to my side of the bed.
Might get interesting.
More seriously, I’ve thought for a long time that PEMF could positively affect Benign Prostate Enlargement.
Maybe judicial application of PEMF would give (the males) among us a twofer and a bit of incentive to try.
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Beth
#10
I saw him in an interview basically saying he started the penis topic just to get attention… and it worked.
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AnUser
#11
Does this sound like he did it just to get attention? Queued up at 73 seconds… watch for 40 seconds.
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Bicep
#12
I remember a while back there was a deal where he was betting on how long he would live. I decided it wouldn’t benefit me because he is 20 years younger than me and would outlive me anyway. Now I’m thinking I should make the bet for my estate since it could be the best bet out there.Lol, so does anybody remember the terms or if he’s still doing it.
Looks to me like he’s going down the same speed as the rest of us, just looks a little better on the outside during his slide.
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Same, I am convinced we will eventually get something that gets injected every once in a while like GLP1 and has a more profound effect on longevity and rejuvination than any amount of exercise, red-right therapy and monitoring.
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Nick1
#14
As much as Bryan Johnson has popularized the longevity movement (probably with hidden motive of letting his followers finance his grandplans in quest for immortality), he somehow got possessed by it and clearly named his branded EVOO as “snake oil”.
Sadly, history seems rife with Dr Zolmans and such…
During Victorian Era of Medicine, a young surgeon Dr Joseph Lister was committed to mental asylum when he postulated that germs were the cause of infections in labor wards leading to high maternal mortality.
More recently, Dr Eric Topol was ejected from the prestigious Cleveland Clinic when Merck didnt like what he said about high cardiovascular mortality from their blockbuster pain drug, Vioxx.
One has to wonder if Bryan Johnson’s establishment did the same to Dr Zolman when he questioned BJ’s obsessive views…to declare him insane!
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Oliver signed an NDA with me back in 2021 related to our senolytic formula. Very smart and ambitious guy who never actually practiced medicine. He became highly curious about longevity right out of Med school did not do an internship and decided that longevity is what he wants to work on.
He did start a supplement company on his own with a Resveratrol product he sourced from France. His only “marketing” strategy was price, he felt that was all that mattered with respect to marketing and eventually he put all his inventory up for sale at a deep discount as he had no marketing expertise.
He started a Whats App group “Evidence-based Longevity” that he left, due to his no nonsense approach and had no patience for questions that did not fit in his wheel house. That group still exists and I visit it once in a while. I asked too many of the wrong questions and he banned me
The Admins that took it over allowed me back in 
He is a no nonsense type of person with low tolerance for taking action with interventions that are not supported by RCT’s so I was wondering how long his relationship with a huckster like BJ would last. I found Oli to be very difficult to have a conversation with if you did not agree with him. It seemed very difficult for him to entertain ideas that he disagreed with and his first instinct seemed to be complete separation from any person wanting to discuss things like that.
I did get to help him with a better understanding of electrical stuff related to tVNS and he wrote up a little N=1 protocol for me that I included in early versions of my tVNS instructions
About 4 years seems to have been his tolerance limit
It was much shorter with me and quite a few others LoL!
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I would guess this showed up in the Trudiagnostic Symphony tests. Mine are much higher than I’d like to share and I don’t have nearly as much skin in the game as BJ does.
Probably why the Rejuvenation Olympics does not show those results as they had planned to do.
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He sounds wonderful (not).
I think it is useful for smart people to work with smarter people at the beginning of their careers to learn humility.
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Tim
#18
It’s hard for a self-appointed savior to be humble.
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Nick1
#20
Speaking of longevity, how old is he biologically?
Humility comes with age…
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