#2160

Yes, the non-linear effect is interesting and relevant. That could mean a significant difference in LDL-C for many people if they had zero cholesterol intake rather than what they’re consuming now. Many studies doesn’t take into consideration baseline dietary cholesterol intake.

I think that along with my low saturated fat intake keep my apoB even drug free around ~75 mg/dl.

2 Likes
#2161

I also wonder about the exact meaning of baseline intake. Monthly average? After all, the dietary intake is an impulsive signal, not a continuous one.

#2162

If you can provide reasons for this I would like to know. Thanks.

#2163

How long have you been taking Doxy 50MG and how many days per week? Anything good/bad to report?

Thanks,

#2164

I’ve been taking it daily for several years. Seems to help with dry eye… otherwise nothing to report

4 Likes
#2165

I originally started taking doxycycline as part of my anti aging stack after reading the following 2017 article by M Blagosklonny.
From rapalogs to anti-aging formula | Oncotarget
50mg since I didn’t want the full antibiotic dosage, since that’s not why I use it.

5 Likes
#2166

Yoooo this is my first time testing these markers. This is pretty damn good right?

image
image835×315 30.9 KB

5 Likes
#2167

If I’m reading this correctly, converting it to units used in the US your ApoB is 59mg/dL, and ApoA1 is 135mg/dL. Together with very low Lp(a), these are pretty stellar values. If your hsCRP and IL-6 are low too, I think you’re in a pretty good spot, assuming your trigs are not out of whack.

5 Likes
#2168

hsCRP 0.7mg/L
IL-6 I have never tested.
Triglyceride 0.9 mmol/L

1 Like
#2169

Trigs also excellent (US unit conversion 35mg/dL), decent hsCRP. You’re good!

4 Likes
#2170

Feels good man. From what I hear nothing we can do currently can lower Lp(a), but I wonder if something in my crazy routine did lower it? This is the first time I’ve tested it, or APOB

1 Like
#2171

Berberine + canola oil instead of EVOO decreased my apoB to around a similar level:

Continuing the discussion from Rapamycin and risk of cardiovascular disease:

But prevention of atherosclerosis has benefits to even lower levels.

3 Likes
#2172

I strongly feel tirzepatide and berberine play a big role in my results. I also take citrus bergamot every night. Additionally I’ve been taking D-limonene which I’ve heard is really good for cardiovascular health.

Hard to say which thing is causing this.

Funny how the blood test says my APOB is low. Maybe I need to go on an APOB boosting regimen haha (joking)

3 Likes
#2173

For d-limonene, I simply consume citrus peel daily at breakfast (mandarin, orange, or both). I’ve been doing this for a few years now. FWIW, I have not detected any effect on blood lipids that I could tell.

1 Like
#2174

I picked up d-limonene from some TRT guy who claimed it helps with cardiovascular health while on TRT. It’s a very cheap supplement so I will continue.

1 Like
#2175

DT-109 peptide prevents arteriosclerosis.

2 Likes
Peptides / Bioregulators
#2176

A new video by Gil Carvalho of Nutrition Made Simple! about the benefits of aged garlic extract for reducing plaque:

(I’m sure the topic has been mentioned again and again on this forum, so there likely isn’t anything new.)

4 Likes
#2177

Thx for posting because using aged garlic is new to me. I didn’t watch the video… do you know if this has to be a supplement (which I’m not keen on adding), or can it be in food form?

1 Like
#2178

…and it’s orally bioavailable

And a pharma company has jumped on it:
https://www.diapin.com/dt-109

2 Likes
#2179

Aged Garlic Extract (AGE) is garlic that has been aged for many months. One could make it oneself, probably, but would have to wait for 2 years for it to age.

It’s chemically different from just ordinary garlic or garlic powder. As I understand it, AGE has very little allicin; but contains metabolites of allicin that have health benefits. Allicin is what makes garlic burn when you eat it, and also gives it its smell. AGE doesn’t have that characteristic smell. In fact, it’s odorless.

You can buy it online or even in Vitamin Shoppe in pill form.

I have seen some videos on the web about some interesting other properties of raw garlic (and probably also garlic powder) that might not hold for AGE. e.g. I saw a video a year or two ago about how you can put your feet in crushed garlic, and then eventually you’ll smell and taste garlic in your nose and mouth. The allicin can make its way through your bloodstream all the way from your feet, which must mean that allicin has good skin permeability (and may serve as a permeabilty-enhancer similar to DMSO).

…

Now about that video: it’s made by Gil Carvalho, as I said. He’s considered well-respected and skeptical, and is one of the few people that Brad Stanfield really looks up to for health information. Matt Kaeberlein is maybe another hero of his.

The video has some incredible findings, though Carvalho takes a cautious stance and says the expected things about “checking with your doctor” and that it shouldn’t be seen as a replacement for medicines or doctors – it could be considered an “add-on”, though more studies are needed to confirm its effects.

One of the studies Carvalho mentions showed that diabetics (control group) saw an increase in “low attenuation plaque” by 57% in one year, while diabetics who took a sufficient amount of AGE saw a 29% decrease in low attenuation plaque. That’s a MASSIVE difference!

4 Likes