Common blood pressure drug slows aging and boosts lifespan, even in older animals

Joseph · 2025-06-12T16:46:08.775Z

Common blood pressure drug slows aging and boosts lifespan, even in older...

A drug used for high blood pressure, known as rilmenidine, may also be effective in slowing the aging process, even in older animals.

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Rilmenidine

2007, xPharm: The Comprehensive Pharmacology Reference

https://www.sciencedirect.com/topics/medicine-and-dentistry/rilmenidine

lukegadget · 2025-06-12T17:20:19.586Z

I tried to get a prescription for this last year, and it’s basically unavailable in the US.

To get it I’d probably have to go to one of the Indian suppliers.

Stiv · 2025-06-12T19:42:12.940Z

Interesting. Doesnt even appear in the UK drug ‘bible’, the BNF.
Says alcohol is not to be consumed with it. Rules me out😎

EverVital · 2025-06-12T19:57:30.275Z

PubMed Central (PMC)

Rilmenidine extends lifespan and healthspan in Caenorhabditis elegans via a...

Repurposing drugs capable of extending lifespan and health span has a huge untapped potential in translational geroscience. Here, we searched for known compounds that elicit a similar gene expression signature to caloric restriction and identified...

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adssx · 2025-06-12T20:16:51.048Z

See: Rilmenidine Extends Lifespan and Healthspan by 20%

adssx · 2025-06-12T20:16:54.168Z