FWIW, I took Tirzepatide for several weeks with no side effects.
It killed my appetite for months after I stopped taking it.
For me it was the opposite. I had severe side effects especially back pain to the point of walking crooked. I stopped Tirze and started Reta and the pain has started to get better. As far as appetite suppression, I thought they both had about same effect, they basically did what they were supposed to, but with RETA I would get the feeling of being full faster, and often times would leave food on the plate (never happens in real life).