#1

Health Rising just posted that a lady with treatment resistant osteoporosis was using low dose naltrexone and Rapamycin and had a significant increase in bone density. She was doing other things so can’t be sure that was it, but found it interesting.

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#2

Excellent! Thank you for sharing.

I started LDN within the last couple of months and had a dexa in the fall. I’ll share if I should see something interesting when I get my next one. I did start taking calcium, so it might be hard to know what to attribute any gains to?

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#3

I’m on my third week of rapa as of tomorrow and I am also using ldn, specifically because of that case report. I had a Dexa right before starting, so I will try to get another in a year or two.

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#4

Beth and Nio do hope you’ll check back in!

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#5

In one year after taking AlgaeCal Plus plus wearing a 12 pound weighted vest while running/walking, my bone density scores (on the same machine) improved as follows:

  • Lumbar Spine (L1-L4): +8.0%
  • Left Femoral Neck: +6.4%
  • Left Total Hip: +6.1%
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#6

Wow that’s great! Definitely best if can do without drugs. Did you add any resistance training? Health issues keep me from doing much but do take algae cals collagen and another algae product but not their brand.

#7

Beth do you know about needing K’s with your calcium so it doesn’t settle in your arteries?

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#8

I do some push ups and planks but not a ton.

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#9

I do, but I appreciate you making sure!!! Thank you!!!

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#10

In two years I have reversed my osteoporosis (7.6% increase in bone density in neck of femur) using only MHT (oestrogen, progesterone, testosterone), OsteoStrong once a week, Kieser 2-3 times a week, increased calcium intake via fortified plant milks. No bone drugs. My doctor said it couldn’t be done without bone drugs!

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#11

That’s great Lynn! I looked up Kieser and seems to be in Australia? However there’s an Osteostrong not far from me. My problem is health issues and significant fatigue so can’t really commit to that kind of thing. Do need to get in gear and do what I can when I can here at home though. The HRT I’m almost certain is what kept my bones stable from age 60-67, but haven’t checked since and now 71. Just wish the doctors had been more educated years ago and put women on HRT in perimenopause, course even now a lot of doctors won’t do it. Just read today in Ronald Hoffman’s newsletter (doc in NYC) that the osteoporosis drugs if taken too long can have a rebound effect and make bones more brittle. This interested me because my mom, who lived to 92, had several nasty falls and never broke a bone but her cousin took fosomax and fell several times, always breaking a bone.

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#12

Just chiming in with a few thoughts:

  1. Love your success. I can’t stand when docs say ‘it can’t be done’, because there’s so much resilience in the human body and so many unknowns to medicine.

  2. For the person who is too fatigued to do bone strength exercises, consider getting a vibration plate with hand rails. There’s some evidence that it can strengthen bones and one only need to turn it on and stand there.

  3. There’s a case report that shows Rapamycin with ldn had a good effect on a 53 yr old woman with osteopenia. It’s been discussed recently on this forum.

Keep these anecdotes coming! They are inspirational to many of us.

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#13

Hi Nio, I can’t use a vibration plate because I have a condition called Superior Canal Dehiscense, basically a hole in the ears. Had a craniotomy for one in 2010 and trying to keep the other at bay. I did use one once and had vertigo for a week. There’s the Marodyne that a Clinton Rubin invented that’s very low frequency but recently it’s come out that his claims aren’t true, and that one does need something like a power plate. I’m really not even supposed to lift more than 10 pounds but suppose that’s all I’m capable of anyway for most exercises. Asked the doc about this and he said main thing is remember to correctly breathe while doing the exercises, if I would go over 10.

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#14

Long with borderline osteoporosis in hips and wrists, I have improved much since jumping down from a 40 cm structure landing on one heel at a time varying between different directions, respectively arresting falls against a wall with the back of my hand.

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#15

Ulf, this sounds interesting. I assume these are things you just designed on your own. If you have any more details I would like to know.

#16

A good overview video on the topic:

This video explores how to build and maintain strong bones throughout life, prevent osteoporosis, and highlights the benefits of resistance training for bone health.

Here are the key points from the conversation between Peter Attia and Belinda Beck:

1. Bone Health Across the Lifespan

  • The foundation for strong bones is established in childhood and adolescence, making early life a crucial period for bone health. Maximizing bone mass during youth is essential, as it sets the stage for bone health later in life. ​⁠
  • Osteoporosis is described as a “childhood disease” because the risk is largely determined by the peak bone mass achieved in youth. ​⁠

2. Physiology of Bone

  • Bones adapt to mechanical loading (Wolf’s Law): bone structure and strength respond to the forces placed upon them. ​⁠
  • Osteoblasts build bone, while osteoclasts break it down. The balance between these cells changes with age, favoring bone loss in later years, especially after menopause in women. ​⁠

3. Optimizing Bone Health in Children

  • Key factors: adequate calcium intake (about 1,000 mg/day for teens), sufficient vitamin D (from sunlight and diet), and regular physical activity, especially weight-bearing and high-impact sports. ​⁠
  • Sports like gymnastics, basketball, and soccer are particularly beneficial for bone health due to their dynamic, high-load, and varied movements. Swimming and cycling are less effective for bone density. ​⁠
  • Resistance training is safe for children and does not stunt growth; teaching proper technique is important. ​⁠

4. Bone Health in Adulthood and Aging

  • Maintaining bone health in adulthood relies on continued physical activity, especially resistance and weight-bearing exercises, and a balanced diet. ​⁠
  • Bone loss accelerates during menopause due to the drop in estrogen, which normally inhibits bone breakdown. Hormone replacement therapy and exercise can help mitigate this loss. ​⁠

5. The LIFTMOR Study

  • The LIFTMOR study tested heavy resistance and impact training in postmenopausal women with low bone density. The program involved 30-minute sessions, twice a week, focusing on compound lifts like squats and deadlifts at 85% of one-rep max. ​⁠
  • Results: Significant improvements in bone mineral density (especially at the spine), muscle strength, posture, and quality of life. Some participants were able to deadlift their body weight. ​⁠
  • The study also found improvements in cortical bone thickness and functional outcomes like balance and grip strength, which reduce fall and fracture risk. ​⁠

6. Practical Guidance

  • For those at risk of osteoporosis or with low bone density, supervised high-intensity resistance training is highly beneficial and safe when properly coached. ​⁠
  • Programs like ONERO, delivered by accredited physiotherapists or exercise physiologists, are recommended. If access is limited, telehealth consultations or supervised gym programs are alternatives. ​⁠

7. Broader Impacts

  • Beyond bone density, resistance training improves independence, posture, confidence, and overall quality of life in older adults. ​⁠
  • Exercise is emphasized as the most potent intervention for healthy aging, surpassing any pharmaceutical option. ​⁠
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#17

Hi Jay, the exercises were developed by physical therapists, showing fine results on BMD (can´t find the article).

You start with a low height and move up, to see you can handle it. When I hit 46 cm height one foot got hurt and I found 40 cm to be fine.

I jump upwards before descending. Landing on one heel. I jump twenty times straight forward, alternating between left and right after each jump so ten on each heel.

Do the same jumping 45 degees to the right and left. Total ten on each heel, never the same heel twice in a row.

Finally the same sideways, to right and left.

For my wrists, stand as far as I can from a wall, and fall forwards, arresting the fall with the wrist of one hand. Change between left and right after each fall. 30 for each wrist.

I am not aware of any exercises that equal these in effectiveness for the hips and wrists. .I have no osteo in my spine.

I did OsteoStrong for one year and it had no impact on me, as measured by the Dexa scans.-

I wish you good luck!
Ulf.

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#18

Since the force of impact travels upward, wouldn’t a body in alignment see improved scores from ankles, knees, hips, and spine? Likewise, from the wrist to the elbow and the shoulder?