Interstitial Cystitus-overactive bladder

PJSnyder · 2023-10-02T18:59:16.221Z

Greetings, new user, I started Rapamycin about 1 month ago (6mg week).

I have always had a problematic bladder, what they call interstitial cystitis and overactive bladder. I feel a change in urination especially on day 1 and 2 of my dosage. I believe the IC may be improving, but no relief yet regarding the overactive bladder (or urgency). I would be happy if either symptom was reduced. Anyone else have overactive bladder?

Lia_Az2024 · 2024-03-15T19:49:35.347Z

Is this still helping with your IC? I’ve had IC for 20 years and it’s getting worse. I’m open to trying anything to help. Thanks!

Joseph · 2024-03-15T20:38:10.855Z

FWIW

"Intravesical dimethyl sulfoxide (DMSO) for interstitial cystitis—a practical approach"

https://www.sciencedirect.com/science/article/abs/pii/S0090429597001817

Dr.Bart · 2024-03-16T06:24:33.418Z

Interstitial cystitis is not a disease of aging. I am not sure how rapamycin may help here.

There is a good number of proposed treatments, none of them great.

PubMed Central (PMC)

An update on treatment options for interstitial cystitis

Interstitial cystitis or bladder pain syndrome (IC/BPS) is a chronic pelvic pain syndrome related to the urinary bladder. The ideal treatment should match as much as possible with the pathophysiologic causes of the IC/BPS, but the scarcely available...

KarlT · 2024-03-16T16:14:02.858Z

Dr.Bart:

Interstitial cystitis is not a disease of aging. I am not sure how rapamycin may help here.

Because Rapamycin is a cure all.

PJSnyder · 2024-03-16T16:50:12.614Z

I have added daily D mannose (2000mg) . My IC always resulted in UTI’s. Must take daily. I have not had a UTI for over 1 year. You can get the powder in bulk from bulksupplements.com.

Dr Wright, a great resource. https://www.mensjournal.com/pursuits/kim-alexis/d-mannose-a-phenomenon-in-uti-treatment-see-the-amazing-story

Dr.Bart · 2024-03-16T17:12:21.012Z

KarlT:

Because Rapamycin is a cure all.

I hope you are being facetious.

KarlT · 2024-03-16T18:03:12.098Z

Dr.Bart:

I hope you are being facetious.

Very much so. I feel bad for anyone with a difficult health problem, but I am also troubled by how many people turn to Rapamycin to fix anything and everything.