https://www.sciencedirect.com/science/article/abs/pii/S1568163724002149
Abstract
Lithium therapy received approval during the 1970s, and it has been used for its antidepressant, antimanic, and anti-suicidal effects for acute and long-term prophylaxis and treatment of bipolar disorder (BPD). These properties have been well established; however, the molecular and cellular mechanisms remain controversial. In the past few years, many studies demonstrated that at the cellular level, lithium acts as a regulator of neurogenesis, aging, and Ca2+ homeostasis. At the molecular level, lithium modulates aging by inhibiting glycogen synthase kinase-3β (GSK-3β), and the phosphatidylinositol (PI) cycle; latter, lithium specifically inhibits inositol production, acting as a non-competitive inhibitor of inositol monophosphatase (IMPase). Mitochondria and peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) have been related to lithium activity, and its regulation is mediated by GSK-3β degradation and inhibition. Lithium also impacts Ca2+ homeostasis in the mitochondria modulating the function of the lithium-permeable mitochondrial Na±Ca2+exchanger (NCLX), affecting Ca2+ efflux from the mitochondrial matrix to the endoplasmic reticulum (ER). A close relationship between the protease Omi, GSK-3β, and PGC-1α has also been established. The purpose of this review is to summarize some of the intracellular mechanisms related to lithium activity and how, through them, neuronal aging could be controlled.
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Lithium has been in my mineral stack for 2 years now. In Canada it’s a prescription drug so it took me a while to find a reliable source 
There are some interesting studies on natural lithium content in drinking water. It appears to lower all cause mortality.
Trace lithium in Texas tap water is negatively associated with all-cause mortality and premature death
https://cdnsciencepub.com/doi/abs/10.1139/apnm-2017-0653
Low‐level lithium in drinking water and subsequent risk of
dementia: Cohort study
https://onlinelibrary.wiley.com/doi/pdf/10.1002/gps.5890
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