Interesting interview - I watched this and invested in his stack (although I had to put it together myself as his company is in Canada and doesn’t ship to Australia) which is basically coq10, R-ALA, Green coffee extract, green tea, Forskolin, vitamin E and Beet Powder. These apparently interact synergistically. You take these twice a day with a protien shake once a day with a special ratio of whey to casein. The shake also has creatine and calcium.
It takes awhile for him to get to the suppliments as he is rabid about sun and exercise.
I would love anyones thoughts on this, my results have been mixed with a few problems, and I am wondering whether it might be something else–I have been on Mayvet for HepC–and if I should continue?
https://www.youtube.com/watch?v=2j6mUyS2vxI
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I am only on the CoQ10 and the creatine. I heartily endorse the CoQ10, but if you go higher than your body needs for any length of time, it will give you insomnia—which sucks because it feels awesome on high doses, but not sleeping is too high of a price. So if you feel good from this but start to develop insomnia, I’d try cutting back the CoQ10 first.
As for creatine monohydrate, my gut hates it. I finally settled on only taking one milligram after trying and failing repeatedly to adjust my gut to a higher dose. But I also take Creatine HCL, which I tolerate better. I may phase out the monohydrate once I’ve finished my stock up. One thing about creatine to watch out for if you have POTS or tend toward low blood pressure is that you need to up your electrolytes. Creatine may also make you look thicker because of pulling water into your muscles. Some gain a lot of water weight as a result (and even more if they find they need extra electrolytes to tolerate the creatine). Supposedly Creatine HCL avoids or limits these problems too. Since I have been on some dosage or another of the creatine monohydrate the whole time that I’ve been taking the creatine HCl, I’m not 100% sure what it’s like on just the HCl. (And since my gut had such a terrible time with the creatine monohydrate, the gassy bloating alone was making me look much thicker.)
I used to take decaf GSE, but I seem to be on a lot of supplements that can strain the liver, and my blood tests were starting to get slightly odd. So I cut the green tea.
Not sure if you wanted input on the stack only or on components, but I happened to see this and happened to have relevant knowledge.
I had terrible insomnia when I tried to take CoQ10 in the past. Information in the interview claims that CoQ10 pairs with ALA in a very positive way that made me decide to try it again. This time instead of insomnia I have been sleeping deeper than ever. I also got a boost in energy and a remarkable boost in endurance. Strangely I almost lost the ability to puff myself out. Three, three minute rounds of boxing, three sets of 15 jumping jacks, and three sets 15 ab crunches all done in circuit with hardly any rest and still I could have kept going. Another time my husband held the punching bag as I was boxing and started saying, “keep going another 5 - you can do it!” I laughed and after 5 hits came at the bag so hard and continuous, that he let go and stepped back in shock - lol. Very strange! As for the ‘thickness’, yes I have felt that so it was good to know. I hope it passes. My problem now is that after a month or more on this regime I started showing signs of cognitive decline, forgetting words quite frequently. I also developed the symptoms of posterior vitreous detachment in my left eye. This obviously concerned me and I have stopped everything except Zeaxanthin which I have started taking until I can assess what is happening. As I mentioned I just finished a course of Mayvet. I am hoping that was the culprit but don’t know where to go now? The information in this interview is very compelling, I am wondering if the brains trust here might have any clues about this protocol. Its meant to target mitochondrial health with weight loss, muscle gain and longevity as welcome side effects.
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For anyone interested here is the stack:
Coenzyme Q10 100mg -
ALA 200 mg -
Green Coffee Bean Extract 250mg -
Green Tea Extract 250mg
Forskohlis Extract 63 mg -
Beetroot extract - 250mg
Vitamin E - 200 IU -
All of the above 2 times a day
Whey protien isolate 24gms
Milk protien Isolate 16gms -
Creatine Monohydrate 3gms
Calcium 450mg -
The further list above once a day in the morning
The second list also had vitamin D - but as its spring here and I get out in the sun everyday at noon I do not take Vitamin D as a supplement.
Okay it looks like I might have found the culprit. When taking Mayvet I had trouble sleeping and so was taking half a Polaramine every night for nearly 8 weeks. I discovered Polaramine is anticholinergic with a burden score of 3 (highest score). I suspect this may have caused the forgetfulness which is passing now that I have stopped the Polaramine. I also stopped taking Berberine while I was on the Mayvet as the two together made me feel exhausted. I will add it back today. I hope Mark Tarnopolsky’s stack may hopefully have helped me avoid too much long term damage.
I highly recommend anyone interested in mitochondrial health to look at the interview. He works with people with genetic mitachondrial dysfunction and so seems to really know his stuff. As these disorders are so rare they have to push the weightloss / muscle gain and anti aging benefits of their research to help attract funding. I know that his recommendations have drastically improved my endurance and strength. Now I am off the Mayvet (which was a bit rough but better than the first hep c drug I tried and stopped).
