#1

“To check your rate of aging, do periodic biopsies and measure the rate of the accumulation of these mutations”

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https://x.com/hsu_steve/status/1955409648221057368#m

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https://x.com/hsu_steve/status/1934046031307587592#m

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https://x.com/hsu_steve/status/1955409651110945023#m

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#2

Yes, this tracks with my understanding of inherent aging process being the result of design. Mice have crappy design, naked mole-rats a better design and so on. To really make headway against stochastic mutations, you need a corrective mechanism. Perhaps multiple copies of information and a mechanism to compare. Women have XX chromosomes, which provides some redundancy compared to XY. Information loss and repository integrity. But look at bacteria that can keep strains going indefinitely - extrapolate that across all tissues.