In this study, the researchers investigated the long-term effects of nicotine by adding nicotine to mice’s drinking water at low or high doses starting when mice were 8 weeks of age and continuing for 22 months. In aged mice that received nicotine, the researchers observed increased locomotor and general activity, enhanced motor strength and endurance, and reduced anxiety-like behaviors compared to aged controls, especially in mice that received higher nicotine doses. The researchers reported that the behavioral patterns of aged mice that received the highest dose of nicotine were most similar to those of the young mice. Also, postural dynamics, which assess how the body maintains balance and stability, of nicotine-treated aged mice showed patterns more similar to those of young controls.
In this study, the researchers investigated the long-term effects of nicotine by adding nicotine to mice’s drinking water at low or high doses starting when mice were 8 weeks of age and continuing for 22 months.
In aged mice that received nicotine, the researchers observed increased locomotor and general activity, enhanced motor strength and endurance, and reduced anxiety-like behaviors compared to aged controls, especially in mice that received higher nicotine doses. The researchers reported that the behavioral patterns of aged mice that received the highest dose of nicotine were most similar to those of the young mice. Also, postural dynamics, which assess how the body maintains balance and stability, of nicotine-treated aged mice showed patterns more similar to those of young controls.
A counterpoint to this is I found even nicotine gum use to be addictive and use escalated to many times a day.
It was very mentally stimulating and can function as a nootropic but I decided to quit use.