The interesting question is whether it is possible and/or advisable to get the body to improve its creation of peptides endogenously. I am not sure how this might be measured.
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LukeMV
#659
It’s Matthew McConaughey in Wolf of Wall Street.
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TA1 is wonderful and I’ve recommended it a couple times here. I just used it again for the 5th or 6th time this year to avoid getting sick from kids in my house and people at work. It’s a miracle drug. My wife and I start injecting it the second we’re exposed to a virus or notice any symptoms. We used it prior to international travel also. It’s amazing to simply not get sick anymore.
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Agree that people with possible symptoms of mitochondrial dysfunction seem to benefit the most. I did once note that my eGFR improved on 5mg/day for 25 days, and I know of another who had moderate CKD and improved a lot on about 100 mg/week for a month or two.
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Ulf
#662
After several failed attemps at boosting my abysmally low lymphocyte count, this increased 150 % after three recent rounds of Thymosin Alpha 1. My neutrophil/lymphocyte ratio went from 8 to under 3.
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Do you know off the top of your head what the neutrophils and lymphocytes were prior to the TA1?
@ConquerAging interviews Kenneth Scott about peptides. They are trying to reproduce the results from Dr. Khavinson from Russia.
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Ambient
#665
Thanks for posting this. A lot of red flags in that video clip.
Those peptide capsules have been on the market for a long time through various online vendors over the years (or decades) IIRC, such as Swansons vitamins, International Anti Aging Systems, and other places.
I try to follow various sports & athletics.
I’ve never heard anyone mention this products in high regard compared to injectable peptides.
Here is a list of products banned by Wada:
These products are not listed.
Kenneth in the video mentions various things like:
-peptide products come in a pack of 20 capsules @ $45, he takes 5-7 different peptides a month.
2 caps a day for 10 days, then that’s it. Around $350 a month (USD)
Every month takes 5-7 different peptides of the product line.
Difficult to say what the impact is. Sometimes they see specific improvement. Visoluten(vision peptide) helps his vision a bit. Can read newspapers, struggling a little bit, without his readers(glasses).
Sometimes can see profound impacts quickly.
Cannot measure anything specifically.
One thing they mentioned in the studies, is if you took the program for 3-5 years, that your survival rate was double or triple than that of your peers group.
$350 a month is very expensive for products that one cannot measure specifics, or see profound impacts. Double or triple the survival rate mentioned is a huge red flag.
One could spend $350/month on products from the wada banned list and see profound effects in just the peptide + hormones section.
Or it could buy most of the ITP products that show life extension.
Marketing people also lie about effects of various stuff, when they are also using other medicines that give a bigger effect than the product they are marketing (ex: some peptide or supplement raises my libido, sex hormones or muscle mass etc… but they are also using high dose testosterone and don’t share that information etc).
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I feel the same way on this topic of effectiveness of any substance that is touted as enhancing any aspect of performance related health. If it’s not on the WADA list I don’t want it 
Other than the GLP1-R we use, most are on the list
Love my BPC+TB+MOTS-c combo for breakfast
And our CJC+Ipa+Epi night cap before bed.
During our last week off the CJC+Ipa+Epi dose I found my sleep was not as good. I never really paid much attention to that. We just re-started and after only 2 nights I can already notice the improvement.
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cl-user
#667
That’s impressive! Don’t you get any bruises or other issues at the injection sites with that many repetitive injections?
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I’ve not had any issues with bruising unless i hit a blood vessel and that is quite rare. Been doing 2 to 4 injections a day for 18 months now and not one issue.
The Boss, she is more prone to bruising but even she has maybe 1 little bruise a month, if that.
We use a 32g needle so it’s pretty innocuous.
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The needles used are typically insulin needles. “Nearly all of the 1.6 million Americans with type 1 diabetes require daily insulin since their bodies produce little or no insulin.”
Many diabetics require more than one shot daily.
The point is that these insulin syringes use tiny needles and usually don’t cause any bruising.
I have taken over 200 peptide injections so far using disposable insulin syringes, and maybe one out of every 100 injections causes any bruising.
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Ulf
#671
The chart shows my lymphocyte count, measured in European SI units. Reference range 1.1 - 3.5. Three rounds of Thymosin Alpha 1 between the last two measurements, 0.4 and 1.0.
Neutrophils went from 4.3 to 2.8 for the samt points in time. They used to be around 2.8 so the 4.3 number could be an outlier. If one uses 2.8 as the base value my N/L ratio went from 7 to 2.8.
Am ordering more TA1 to see if I can get up my lymphocyte count further.
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I have lower lymphocytes(around 3). My nlr is around 2. It’s nice to get someone else’s data. Thanks
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Ulf
#673
[quote=“cl-user, post:667, topic:11956”]
Don’t you get any bruises or other issues at the injection sites with that many repetitive injections?
Almost never, not even with deep intramuscular injections. In the belly for SubQ, in the glutes for IM or SubQ (GHK-Cu, got burn when done in the belly). Only time I got problems was with injections in the thigh.
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Tim
#674
What’s your dose for thymosin?
I’ve tried everything from the Zadaxin protocol (1.6mg 2x per week)…
to loading doses of 3mg, then 2, then hold at 1 until vial empty (step down each day)…
to 1 mg am, 1mg pm for a couple days, then 1mg until vial empty…
to 1 mg/day from day 1.
It depends on whether I already feel a touch of illness or am taking it prophylactically.
It’s safe at higher doses and many references are here:
Thymosin alpha 1 is usually found in an injection form and is commonly prescribed by a primary care physician. Thymosin alpha 1 is usually administered twice a week via a subcutaneous route. The standard single dosage ranges from 0.8 to 6.4 mg, while multiple doses range from 1.6 to 16 mg for five to seven days. Utilized in various illnesses such as liver disease, cancer, and autoimmune diseases, thymosin alpha 1 has been shown to be well-tolerated and safe[34].
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Ulf
#676
After recently having reported on my immunity being restored by a wonderful peptide, thymosin alpha 1, I now have a terrible story to tell on another peptide, BPC-157. I could scarcely think after taking it and had to quit working that day. I can´t recall that having happened before and I dare not try a second time.
The horror stories from BPC-157 are mainly mental, and those who give their history have had neurological issues of some kind. It is speculated that it can mess up neurotransmitters. On my part, I have been on an SSRI since 25 years.
I am most grateful to the two members of this Forum who alerted me to the dangers for a (small) minority of users of BPC. Probably thanks to this, I started very low at 100 mcg subQ. Next evening 200 mcg and the next morning it hit me, for one day. Next day I was back to normal…
Am I glad I didn´t go for the normal 500 mcg. Lesson learned I will check any new substance for horror stories and if they exist start real low.
Will instead try TB-500, a synthetic derivative of Thymosin Beta 4, to heal a persistent muscle injury.
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I think it is possible that the body when functioning optimally generates peptides. Hence it is entirely possible to overdose on these.
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