#36

I see that he hasn’t made a video about peptides yet, maybe you can ask him his opinion on the peptides TB-500, BP-157, GHK-cu, MOTS-c, SS-31 ?

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#37

Has he updated his opinions on any of the products reviewed some time ago, e.g. methylene blue.

#38

If I guess he’s good about mitochondria:

Attia speaks a lot about Zone 2 exercise to improving mitochondrial function, does this happen systematically or is it just in the muscles exercised? Which areas of the body has an improvement in function or density of mitochondria because of Zone 2? Might organs have these improvements? Is there any way for the body to transport mitochondria elsewhere? Might Zone 2 improve density/function of mitochondria in i.e the brain directly from exercise or even transport?

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#39

A deeper look into taurine

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#40

Key points:

  1. Collagen supplementation works great for skin and joints.
  2. Resistance training reduces collagen breakdown.
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#41

Top 4 supplements eveyone should take:

  1. Creatine Monohydrate
  2. Caffeine
  3. Whey Protein
  4. Omega-3s
1 Like
Which supplements are good for ALMOST EVERYONE?
#42

Creatine, yes. I use both the kre-Alkalyn version and sometimes regular creatine monohydrate. This since almost all serious research has been done on the monohydrate version. But for for me, I get a more positive feeling after ingesting the Kre-Alkalyn version of creatine. Kre-Alkalyn was once marketed to have better bioavailability, but that claim has been debunked. I can only speculate why I get this more positive feeling. Maybe it is as simple as the fact that I get a tiny bit of gastro upset from the monohydrate. Since the PH value is different, I speculate that my positive feeling from the Kre version of creatine has something to do with the difference in PH value and effect on the gut-brain axis. Who knows? But if someone, like me, gets a bit of stomach upset from the creatine monohydrate, then the Kre version could be a more expensive alternative.

And on the above list of four, I would change Whey protein to Collagen. And omega-3 to curcumin.

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#43

Which is why it is probably best not to limit to 4 items. Both curcumin and omega 3 have merits. They operate in very different ways.

#44
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Rapamycin and Taurine
#45
2 Likes
Which supplements do you think are still worth taking?
#46

NMN a failure in male mice. 9% life extension in females.

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NMN/NR worth taking for longevity?
#47

MMMmmmm…, so, according to the latest research, taking NMN in males presently would constitute a huge leap of faith (considering the lack of significant proven benefits in humans, considering that the recent study came from Sinclair’s lab, a party with conflict of interest).
Yet, about 50% of the world population is female, so the market would still be very large.

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#48

But getting female mice to buy your products is a challenge.

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#49

Well, probably not, the lady mice will simply provide a shop list to the lab guys.
And the lady humans will provide their shop lists to the husbands.

1 Like
#50

I prefer to watch Nick Norwitz (Making Metabolism Make Sense) to Nick Verhoeven (Physionic). They are both very good. Nick Norowitz arguably has the better credentials, Ph.D.+ MD

Their channels have different objectives, so it is not quite the same as comparing apples to apples.

Nick Norwitz:
“He graduated Valedictorian from Dartmouth College in 2018, majoring in Cell Biology and Biochemistry. He then completed his PhD in Metabolism at the University of Oxford in 2021, before attending Harvard Medical School to complete his MD.”

Nicolas Verhoeven:

  • Ph.D. in Molecular Medicine (Cell Physiology)
  • Masters in Exercise Physiology
    (I cannot find on any of his sites where he obtained his Ph.D)

Both use clickbait titles for their YouTube videos, which is the norm. This you can ignore because both have very good content.

5 Likes
#51

Here is my talk with Nic Verhoeven of Physionic. We covered a lot of ground here…I’m still thinking about how to upgrade my own program to take advantage of Nic’s thinking. Happy New Year!

9 Likes
#52

@Joseph_Lavelle 20 minutes in and loving the podcast. Thanks Joseph!!! :smile:

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#53

Great! Let me know how you liked the rest. It was a long one but Nic has a lot to say.

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#54

This is a big guest. Nice job. I’ll be listening to it tomorrow.

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#55

That was an enjoyable discussion, the ending has reminded me about the FMD, maybe I’ll resume the practice next spring; hopefully, I’ll have more body weight.

1 Like