#722

Beth,

Have you seen this video from Ryker Black:

Apparently high doses of Creatine (10g and over per day) can help improve bone density although it can take over 12 months to start seeing improvements. Ryker now takes 15g per day which is also enough to help with cognition.

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#723

Wow, thank you @essexaid for sharing this with me. I had no idea. I’ll watch the video. Creatine is something I don’t take, and yeah, from what I hear, I probably should! (I tried it a couple of times, but unlike seemingly everyone else on earth, I hated the taste in my smoothie!). Thanks again!!!

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#724

Creatine is wonderful. I felt it improve my energy levels and overall wellbeing at 5 g a day.

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#725

Are you sure you were taking only 5mg or you meant 5gr=5000mg?

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#726

Yes. It’s 5 grams not mg. It’s a pretty big scoop. Sorry for the typo. I fixed it.

#727
  1. Creatine
  2. Lutein and Zeaxanthin
  3. Omega 3s
  4. Taurine
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#728

To get maximum effect on eye health, one should add 10 mg Meso-Zeaxantin to lutein and Zeaxantin. But I have not found any reliable source for Meso-Zeaxantin in powder form.

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#729

Jarrow Formulas - MaculaPF has 9 mg Meso-Zeaxanthin in addition to Lutein and Zeaxanthin (20 and 13 mg resp). Cheers

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#730

Thanks, but that is sold in soft gel capsuls. I look for it in powder form only.

#731

In looking up meso zeaxanthin, I’m now going down a too deep rabbit hole and have discovered Unibar’s CapsiClear Capsanthin that, upon first glance, might be a powerhouse ingredient for eyes. They also make a meso zeaxanthin, but because I dont find a product, I’m assuming they sell the ingredient to supplement makers… (a guess).

I’m just sharing this in the event anyone already knows about this.

I’ll also tag @CronosTempi who posted a video about meso (that I have not watched yet).

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#732

Unfortunately this is one of those kitchen sink supplements, which include things you may not want. This includes 10mg choline, which I don’t want and astaxanthin 4mg, which I also don’t want as I already take 12mg in a different supplement.

@Beth - for meso zeaxanthin there is the Intelligent Formula Vision Defender MZ. Another approach I’ve seen is where they simply incapsulate powdered marigold petals (a common source of lutein and zeaxanthin), and estimate that on average you get a given amount of carotenoids, including lutein, zeaxanthin, meso zeaxanthin and various isomers thereof. Again, in buying supplements, it is extremely important to select a reliable brand, because otherwise odds are extremely high you are not getting what’s claimed on the label.

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#733

I started the under-lip pouches since there seem to be many advantages of nicotine, such as the observation that smokers had been protected from the worst of the effects of covid and also Parkinson. One 8 mg pouch a day. Habit forming? Well, a little, but not comparable to the headache if I don’t get caffeine in the morning.

1 Like
#734
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#735
  • Why do you take fisetin (a senolytic) daily?
    Other people proposed taking it for example on 3 days once per month. (And additionally it is in tiny doses in strawberries during summer.)
    Therefore you could cut it from your daily list, but still take it and don’t exclude that substance entirely. So you might still get possible benefits alongside reducing the costs.

→ Weekly not daily
A similar approach as outlined above for fisetin is what I treat many of the supplements I take: instead of daily, I take the recommended daily dose weekly.

My reasoning:

  • cost reduction of course,
  • fewer danger of possible, negative side effects, but
  • still getting some benefits/positive effects of it,
  • reduced chance of interference with the multiple other supplements,
  • reduced chance of the body getting too used to a substance with possible negative effects,
  • I can still raise the doses to daily instead of weekly as I get older, when the substances are perhaps needed in higher doses. (Unfortunately the cleansing of the body (kidneys) might also be worse at older age.)

Thoughts on my reasoning taking many supplements only once per week instead of daily are highly welcomed! Thank you very much in advance!

Examples of supplements that I take only once per week (the “daily” dose):

  • MSM
  • carnosine
  • silica
  • glucosamine
  • chondroitin
  • AKG (AAKG, Ca-AKG)
  • quercetin
  • milk thistle extract (silymarin)
  • artichoke extract
  • citrus bergamot
  • aged garlic extract
  • Lithium
  • carrot juice (100 % pure juice, from certified organic agriculture)
  • mixed vegetables juice (100 % pure juice, from certified organic agriculture)

Generally cycling:

  • ashwagandha
  • goji berries
  • cherries/~ juice/~ extract
  • aronia berries/~ juice/~ extract

→ Quercetin:
Same as fisetin. Do it on special occasions in a reasonable dose for senolytic purpose (cf. trials with dasatinib + quercetin). Other than that cut it off your daily regimen or do it only once per week.
Small doses of quercetin are in many food plants, especially apples, onions etc.

→ What is useful for you/your situation, I cannot say. It depends on your diet/nutrition, age, genetics. You know it.
I personally take a dash of cinnamon powder in my coffee or muesli/oatmeal or shake daily for antidiabetic/blood glucose reduction reasons (though not being diabetic), and every other day aged garlic extract and citrus bergamot essential oil for LDL reduction (too high LDL although not eating meat). But if you don’t have this issue, you won’t need garlic or citrus bergamot.

That being said, I generally would perhaps add taurine and AKG to the daily list. You can just take it in very low doses to keep costs low. I do the same.

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#736

I’m also inclined to go less than daily. The dose response curve for most things is non-linear. And ditto the dose side effect curve. So a low dose is likely to have highest impact per unit taken and low side effect risk.

Another way I look at is: the best strategy us furst avoid all deficiencies. A broad sweep of supplements at a low dose is most likely to achieve that aim.

I take the following weekly or biweekly
methylated b vitamins
vit d, k2
curcumin
boswellia
taurine
rapamycin
rosuvastatin
boron
pycnogenol
ezemitibe
magnesium
choline

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#737

Most wasabi is fake. For anyone interested in real wasabi, here is a Canadian source.

https://wasabia.com/

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#738

Get it before the new 25% tariffs on ALL Canadian goods goes into effect March 4.

Interestingly, this all encompassing 25% tariff is going to be on top of other new 25% tariffs meaning that for steel and aluminum there will be a 50% tariff.

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#739

Thanks for the heads up!

We have a housing crisis here, yet a lot of lumber comes from Canada. This is going to hurt so many people.

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#740

It keeps our beaver population busy :slight_smile:

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#741

For me:

Magnesium oxide - up to 750 mg, which is where my bowels get loose. This is taken for some supplemental Mg, but actually mainly for gut mobility

Creatine - muscle and brain benefits are pretty well described now

Fish oil - I don’t get enough through diet

Vitamin D3 for 6-8 months of the year

A very boring list. I would almost never do plant extracts, herbs etc because there’s no real way of knowing he purity, effectiveness. I’d rather use pharma products which are better studied and where the product quality is controlled.

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