Is there any indication that rapamycin and NAD supplements (e.g. TRU Niagin) are counterproductive?
I cannot see why they are counterproductive. I take a bit of b3 in the normal vitaminer. I have some NMN and NR left, but am not taking them. I threw away some old NR tablets last week. They may help some people, but it seems downstream to me linked to a tryptophan pathway.
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I don’t recall anything off the top of my head, but I’d review this thread: Rapamycin Interactions with Other Food, Drinks, Supplements and Drugs
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