#2787
1 Like
#2788

Perfectā€¦ probably do it in St. Louis.
My son lives near that city.

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#2789

Itā€™s amazing! And I eat nothing like that (almost no saturated fat) and my Calcium score is 300.

2 Likes
#2790

As mentioned earlier. I do think guys need a different kind of diet and possibly meats, fats and high proteins foods, probably worked better with male systems. And perhaps vegan diets work better with womenā€¦ as women naturally have more fat cellsā€¦ as seen in BMI charts.

3 Likes
#2791

Agreed, and not only that but in men the main hormone is testosterone while in woman itā€™s estrogen. Estrogen is found plenty in plant foods, yet testosterone inducing compounds are mainly found in meat. Obviously, non-scientific but practical way of looking at it.

1 Like
#2792

Statin use moderates APOEā€™s and CRPā€™s associations with dementia and is associated with lesser dementia severity in Īµ4 carriers

https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.13543

3 Likes
#2793

@AnUser I support your crusade against LDL and APOE.

You are the most prolifigate at finding articles and studies supporting statin use.

Thank you.

3 Likes
#2794

Iā€™m also a fan of statins, but in very low doses. Iā€™m going to try a very low dose myself (even though my blood markers are all normal).

2 Likes
#2795

Just took my first dose of bempedoic acid tonight. Hereā€™s hoping for no side effects tomorrow.

As an aside, my latest shipment of bempedoic acid costs 7 USD a month from India. In the US, it costs 395 USD.

4 Likes
#2796

Doesnā€™t Bempedoic acid have similar side effects as statins (joint and muscle pain, stomach pain, etc)?

1 Like
#2797

I have been taking BA from de USA. Really this price that you achieved is tempting, but iā€™m hesitant about quality this meds from India, as i didnt find a reliable brand.

B

Blockquote

#2798

Bempedoic acid has statin like properties without the side effects. Supposedly. I will find out.

The brand of Bempedoic acid I am using is called Brillo. Iā€™ll measure my cholesterol at my next blood work and Iā€™ll know if itā€™s the real deal or not. For this price, Iā€™ll take the chance.

Itā€™s made by Sun Pharma which is the largest pharma company in India. That makes me feel safer.

Waking up this morning after my dose last night, I have no muscle soreness.

@LaraPo I was reading somewhere that said you can use bempedoic acid and a statin together. I didnā€™t get too far into that research as statins are a no go for me. But it may be something you can consider like what @Paiva (below) is doing.

2 Likes
#2799

I have taking BA, Rosuvastatin and ezetimibe since 2y ago. Nothing to report except a mild pain in the legs sometimes.

2 Likes
#2800

@Paiva How much has your ApoB, LDL, and TG changed?

#2801

As i have taking rosuvastatin and ezetimibe for long time then, when i start Rapa 3 years ago, my lipids rose. But decresing again w/ BA add. For now, ApoB, LDL and TG it are around 60-70mg/dc. But i increased ( a month ago) Rosuvastatub a little bit, as iā€™m intend put it around 50-60mg/dc, mostly ApoB.

4 Likes
#2802

Bempedoic acid supposedly is limited to decreasing cholesterol synthesis only in the liver and has essentially no effect in extrahepatic tissues, so muscle soreness should not be a thing. Seriously considering ordering from overseas and adding to my ezetimibe/PCSK9i regimen.

3 Likes
#2803

Do you have any sense of how very low dosing of bemp might further lower Apo B if already taking PCSK9i (with or without ezetimibe)?

#2804

Numerically, no I donā€™t, only that I want to get my ApoB down as low as possible with as few side effects as possible. PCSK9i + bempedoic acid + ezetimibe appears to be an ideal combination. My insurance wonā€™t pay for BA since Iā€™m already on the other two and my LDL is already ā€œlow enoughā€ from their perspective.

3 Likes
#2805

Seems Citrulline may help reduce LDL, TC, cytokines and inflammation.

Citrulline group had a notable reduction in FBS (p = 0.04), total cholesterol (TC) (p = 0.02), low density lipoprotein (LDL-C) (p <0.001) and high-sensitivity CRP (hs-CRP) (p <0.001). Also, a significant increase in lactate dehydrogenase (LDH) concentration (p <0.001) was observed in the intervention group at the end of the trial.

1 Like
#2806

I am adding 2 mg rapamycin a week to start with as I am never going to start otherwise.

Currently taking 5 mg rosuvastatin a day and 2 mg rapamycin once a week.

1 Like