Davin8r
#870
It’s important to keep in mind that data from an “N of 1”, while potentially interesting, is essentially worthless when it comes to making broad, sweeping conclusions on any topic in science/medicine. I’d get a calcium scan and regardless of the result, make sure your ApoB is on the low side (more aggressively low if calcium score is high).
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zazim
#871
Yes I should have been more clear. The reason he has 80% on statins is because he wants to get apoB down to 30 or less. Something well below what is considered normal. It’s part of his philosophy that if you want to do all of these things in your last decade then you need to be better than normal now.
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zazim
#872
Agetron, I agree 100%. I haven’t haven’t done any testing since rapamycin but just changes in diet and exercise made a huge difference.
HDL C — 71 to 82
LDL — 195 to 96
Tryg. — 104 to 38
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Agetron
#873
Davin8r -t’s important to keep in mind that data from an “N of 1”, while potentially interesting, is essentially worthless when it comes to making broad, sweeping conclusions on any topic in science/med.
Exactly. I agree, however, many long held medical/science beliefs are coming under scrutiny and when reviewed in a modern context many are outright wrong… rapamycin, cholesterol , statins, TRT.
We are here because we question, push boundaries and do our own testing. Looking forward to a long, healthy friendship here.
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Maybe a useful compromise for the person with CAC zero, but elevated ApoB, would be to still stress diet, exercise, and supplements like citrus bergamot, flax, and Amla. Certainly shouldn’t tell them that their behaviors don’t matter because of the score.
3 Likes
Agetron
#876
Guys… I am not sure where to locate my ApoB in a standard CBC blood test.
Or does that require a special test? Like sirolimus?
José
#877
zazim
#878
It is not very expensive.
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Agetron
#879
Nice… my physician did a cholesterol test that said my lipids are big and fluffy… not small and sticky.
Says mine bounces through… lol.
Jay
#880
MAC, I tried to get my doctor to give me a prescription for a CT coronary calcium scan to no avail. She thinks I don’t need it. I contacted the place that does the scans directly and was told “no, not without a prescription.” Geez! I’ll pay the cost. I’m not sure why they’re so resistant in my area. I’m pretty sure they’re not going to be flooded with requests for scans if they start doing them without a prescription. No rhyme or reason – it’s just they way they do things!
Fortunately, I can easily get bloodwork without a prescription in my area which I’ve heard may not be true everywhere. I’m glad that’s not a problem for me.
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José
#881
Jay,
FWIW, get a prescription{for the CAC] online cost you $70.00 on average. There are many sites available.
Seperate test. I paid out of pocket for one ( I used Ulta Labs) and it is $35.
José
#883
$35.00 for prescription or $35.00 for CAC?{a CAC for $35.00? cost more to operate the scanner]
Sorry, I may have replied to the wrong question. $35 for apoB
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I posted previously that I didn’t think rapamycin had any effect on my lipids. A further study into a more extensive history of my rapamycin vs lipid scores shows that it indeed has affected my lipid scores, especially the triglycerides. My doctor isn’t concerned about the triglycerides.
As for ApoB, recently I came across several articles that indicate remnant cholesterol is a more important indicator than ApoB/.
Fortunately, my remnant cholesterol stayed in the relatively safe range.
My lipid and weight history since starting rapamycin. You can see even though my weight decreased during this period.
https://onlinelibrary.wiley.com/doi/full/10.1111/joim.13059
Study Suggests ‘Remnant Cholesterol’ As Stand-alone Risk for Heart Attack and Stroke)
4 Likes
zazim
#886
What a wonderful chart! Am I reading it correctly? 1st 8 mo before Rapamycin, next 3 mo after?
Slightly confusing because I wasn’t taking measurements as often before I started taking rapamycin.
The first entry is to the far right and is the nearest reading I had before I started taking rapamycin. The last (newest) reading is on the far left taken 60 days after my last dose. In other words, the chart reads from right to left.
hamtaro
#888
If my ApoB is ~95… does it make any sense to follow Dr. Attia’s protocol and take statins to get it down to 60?? I’m really hesitant about this.
My current diet is very heart-healthy, so I feel like I can’t get it much lower with interventions.
José
#889
There are many other compound’s you could try before statins that have been mentioned on this forum.
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