Rapamycin for teeth/periodontal disease

[bru1650]

Hi, I’m new here so maybe this has been covered. I have periodontal disease and was considering taking rapamycin for my teeth specifically bone loss.Has any one taking rapamycin noticed changes in their teeth health and what would be the recommended dosage for this. Thanks

[Alpha]

Use search to find earlier discussion on this.
Adding rapamycin to toothpaste does much.

What evidence do you have of rapamycin affecting bone loss?

[bru1650]

I saw the study that showed increased bone growth in mice in regards to their teeth. I was wondering if anyone else had saw some improvement in that regard, bone growth

[Curious]

My dental pockets improved.

[bru1650]

Thank you for response how much are you taking and for how long

[adssx]

With rapamycin tablets and/or toothpaste?

[bru1650]

I’m not currently takin rapamycin but might consider it in any form if it helps with teeth especially peridontal disease. Just looking for other people’s experiences and what they are doing

[adssx]

Yes I know, my question was for @Curious And welcome here!

[Curious]

I use rapamune tablets. I hope this as a general rejuvenating effect.

[rberger]

Anecdotally I would say my Gums have had almost no pockets when measured by my dentist since I started Rapamycin. I use to have really bad pockets. But I was already on a trend of improvement. So correlation is not necessarily causation.

[DeStrider]

I used to have deep pockets as well. The combination of an anti bacterial toothpaste and Rapamycin did the trick. My gums rarely bleed anymore and no more pockets.

[RapAdmin]

@bru1650

I have periodontal disease and was considering taking rapamycin for my teeth specifically bone loss.

Yes - there is some good research on rapamycin potentially helping with this… studies are ongoing. See these threads:

• DIY Rapamycin Toothpaste and Flossing Paste

• Making Rapamycin Toothpaste - Any Dentists Here for Comments?

[Sadik_Toprak]

Unfortunately, Rapamycin has not treated my periodontal disease. I have received weekly 6 mg of Rapamycin for 5 years. I gave breaks from 3 to 6 months to time.

[RapAdmin]

Welcome to the site Sadik.

You might want to look into topical use (rapamycin toothpaste): DIY Rapamycin Toothpaste and Flossing Paste

[hitch]

I previously posted results from my first cleaning after starting rapamycin. My gaps improved dramatically.

Anti-aging Benefits of Rapamycin, Personal Experiences (part 2)

Rapamycin and Periodontal Disease I went to the dentist for a cleaning yesterday. For several years, I’ve had inflamed gums- based on measurments taken by the hygenist. I have used a waterpik and Sonicare toothbrush for many years, but no improvement. I have now been on rapamycin for seven months and have read the mouse studies that show rapamycin combats periodontal disease. I had high hopes/expectations that I would show significant improvement. And rapamycin delivered! On average, the teeth where the gums had shown the most inflammation had an average improvement near 40%. Happy about that!!!

[LiveLonger]

I also saw my dental pockets improve. In 6 months taking rapa every other week, they moved from 4 to a 3 grade.

[John_Hemming]

I found sucking melatonin reduced gum inflammation.

[splarme]

I am 69 years old and exercise 6 days a week plus Keto and intermittent fasting. I have been taking a 6 mg dose weekly with 3-4 week breaks every 3 months for 14 months now. I have not noticed many changes but I believe in the promise of the longevity research. The one positive I did notice very quickly was less gum bleeding. I have read many other posts saying something similar.

[wrap-a-mice-in]

My gums are noticeably pinker when I’m on it vs. when not.