Rapamycin & hypertension

[DrRoss]

Patient who has blood pressure 160/95 wonders if rapamycin could be causing/contributing to his elevated blood pressure.

My searches don’t yield much. Any comments and/or suggestions from forum members?

[José]

FWIW

Review this thread;

Has anyone seen a rise in blood pressure?

I had been taking rapamycin since August, quickly working my way up to 3mg and then staying there until over the past 6 weeks upping my dose to 6mg weekly. 2 weeks ago, I started having headaches and feeling a bit lightheaded. I stopped taking rapa the following week out of caution. The headaches and pressure and lightheadedness continued through this week along with ringing in my ears. After some googling and consulting Dr. ChatGPT I began to think this might be due to raised blood pressure. I dug out my automatic blood pressure cuff and it read 160/80! Not emergency-room level, but not at all good. And much higher than it has been for most of my life. I am going to carefully monitor my blood pressure and stay off rapamycin at any dose for the time being. If it increases at all, I will i…

[RapAdmin]

Also, some info here: Rapamycin can increase triglycerides, cholesterol, free fatty acids, AND blood pressure? (not in all, but some people) Not to mention blood glucose

and here: Rapamycin with High Blood Pressure/ BP Medications - Anyone with Experience and / or Tips?

[DrRoss]

Here is a link that gives a nice summary of rapamycin for cardiovascular disease from NatureMed in Colorado.

https://www.naturemedclinic.com/rapamycin-dosage-for-cardiovascular-disease-treatment-and-prevention/