This is interesting, and validates that rapamycin prevents cells from entering a scenescent state.
In another experiment, the researchers exposed a new set of spinal organoids to a combination of sodium valproate and rapamycin, finding that senescence didn’t occur. They then replicated the tests in zebra fish larvae, and similarly found that the cells didn’t go into senescence and showed no signs of the changes that occurred when cells were exposed to sodium valproate alone.
Read the full story: https://www.newscientist.com/article/2450476-rapamycin-could-make-an-epilepsy-drug-much-safer-during-pregnancy/
Research paper:
Molecular Psychiatry DOI: 10.1038/s41380-024-02732-0
Valproic acid-induced teratogenicity is driven by senescence and prevented by Rapamycin in human spinal cord and animal models
We next show that the clinically approved drug Rapamycin inhibits senescence and restores aberrant NCC differentiation trajectory after VPA exposure in human organoids and in developing zebrafish, highlighting the therapeutic promise of this approach
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Any time I hear that Rapamycin does something new and wonderful or something validates Rapa’s beneficial effects it gives me a warm fuzzy feeling. 
Considering how much I hate senescence, it’s doubly so. This made my day. 
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