Has anyone been able to achieve a rejuvenation that is REALLY VISIBLY? (not just through blood values or measuring devices)
And how did you manage that?
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I managed to achieve rejuvination of hair. Went from thinning, receding and light-brown to thick, slightly-receding (1cm) and dark. I achieved that by using finasteride 1mg daily for years.
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LaraPo
#3
I think I achieved rejuvenation of skin by sticking to a plant based diet for decades, taking Rapa for 14 years, and applying āgood stuffā to my skin all the time.
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Alpha
#4
More hair - Rapa topically
Better gums - Rapa toothpaste
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JKPrime
#5
I donāt believe any meaningful whole body rejuvenation or age reversal is possible and has ever happened. That said going forward you may be able to a degree slow down aging through calorie restriction and / or rapamycin.
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Hi Elizabeth! Welcome.
Iām almost 52 and have been on Intermittent Rapamycin Therapy for over 4 years. I have given dozens of speeches and presentations to folks in my local Toastmasters Club, and a few other speaking opportunities. I also tell anyone who will listen about Rapamycin. Outside of family, Iāve only convinced 3 people to start their Rapamycin journey and two of them were MDs in ācosmetic practiceā.
The discussions always went something like this: āhow old do you think I am?ā 42 and 44 were their answers.
Rapamycin āSlows down timeā (M. Blagoskionny)
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Ludovic
#7
What dosage do you use for your hair?
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Alpha
#8
Search the site for discussion of this.
I add 8 mg Rapamycin powder from a compounding pharmacist to a monthās supply of Minoxidil.
It hasnāt completely restored what I have lost in my 72 years, but it has taken me back maybe 15 years.
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judy_bb
#9
Where do you get Rapa toothpaste?
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Alpha
#10
At least 3 discussions on this across the forum:
I think RapAdmin started these discussions.
My latest formulation:
I use 6-8 mg of Rapamycin per approximately a month supply.
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When it comes to visible you have skin and hair. I think skin is easier than hair.
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In the past five years, Iāve seen visible reduction or slowing of signs of aging from, in chronological order (1) quitting alcohol, (2) starting HRT, and (3) adding strength training to my exercise routine. I feel and look better (though not necessarily younger) than I did 10 years ago. Thereās also less stress in my life, and I spend more time on self-care than caring for children and aging parents.
Iāve only been taking rapamycin for a few months, so I canāt tell the long-term effects, but I have seen little to no visible results in the short term. My skin is no better and sometimes worse. But Iām taking it to reduce the risk the risk of dementia in light of genetic and familial risk, not for visible anti-aging effects.
Bridget
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blsm
#13
For me and my family itās more like rejuvenation you can Feel. We have been taking rapa since January of 2023. I would say it slows things down for me with regard to the visible signs of aging. I generally feel like I donāt change rapidly in the wrong direction these days. I remember at one point every single day used to feel like there was a new unwelcome surprise in the mirror. One thing I think rapa did was give me the initial boost I needed to start making other helpful changes in areas like diet, exercise, stress management ect. I was running with my dogs through a field the other day and thought of how amazing it was for both myself & my geriatric chihuahua who couldnāt walk in the fall of 2022 to be sharing such a joyful time. That said we all basically look our age but just healthy for our age.
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Just turned 65 and just woke up. Im hanging in there. 2 to 3mg Rapamycin with grape fruit juice weekly, minoxidil 2.5mg oral, Zoloft, Buproprion, Lipitor 1x daily. Ginko biloba, NMN and 15 other supplements daily. Regular cardio and strength exercise. Iām also fortunate to have a stable and happy life. Just had 36th wedding anniversary. I have good hearing aids and looking forward to cataract surgery in a couple months that will restore 20-20 distance vision. I try to use the tools that are currently available. I do plan on looking into any new treatments as they become available and affordable. Im strictly middle class so no big money for expensive therapy and diagnostics.
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Oh, and no face smoothing used on that pic.
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JKPrime
#17
We are of similar age. Now it looks like you are already taking plenty of medicines, so why do you take Ginko biloba, NMN and 15 other supplements daily? Personally Iām less is more mindset as Iām always concerned about drug interactions and potential damage/burden to your vital organs like liver.
Thanks for sharing - Iāve taken the same amount for just a little longer, but still have grays popping up here and there. Maybe I just didnāt have as much as good genetics as you do!
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I believe that supplements add valuable nutrients and positively effect the human body at the cellular level. None of the medications Iām on improve memory. Ginko Biloba is taken primarily for that purpose. Another example is that I take lipitor, which is good at reducing cholesterol, but is know to cause mitochondrial impairment in human cells. I take CoQ10 at 200mg to 400mg because it is beneficial to mitochondria. I take fish oil because itās widely known to be good for the circulatory and nervous systems. I also take berberine which reduces my blood glucose levels, which in the past have been over 100 mg/dL. I always test in the 80ās to 90ās now. For me, it works just as good as metformin, without a prescription.
My view is that more intervention does more good than harm, as long as obvious detrimental interactions between drugs and supplements are avoided.
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Ginko is a Yanq Qi herb as part of TCM. As far as I can tell all Yang Qi herbs activate AMPK which is useful from time to time.
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I had extremely thick hair as a child which DHT started destroying ever since I turned 15. So no, my genetics were terrible for balding but finasteride proved to be even more powerful than that.
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