#161

Thank you for bringing this to my attention. Was not aware of it. Let me investigate. Tx Cheers

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#162

Wow. Thatā€™s way down town.
The machine that measures your insulin is obviously newer/more accurate than the machine that analyses mineā€¦it has 2 IU as the lower limit of detection. So mine just come back as ā€œunder 2 IUā€.
Fasting or post-prandialā€¦still under 2.
My GP nearly fell off his chair.
I take metformin and Sirolimus that might have some effect, but not much else. I have a sister who is very similar to me so it might be a genetic thing.
I find I need to eat at regular times or I quickly get weak and then a headache.

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#163

Haha every time I see some Bryan Johnson level protocol I get radicalized.

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#164

Why go there for only a pound? Not worth the risk of accidental OD.

You could add Retatrutide to your Tirzepatide.

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#165

It kind of sucks to know I probably havenā€™t been getting the benefits of Telmisartan beyond blood pressure by only taking it at 40mg for over a decade. Whenever I went higher, I wouldnā€™t be comfortable with my blood potassium levels being north of 5

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#166

New high blood pressure guideline emphasizes prevention, early treatment to reduce CVD risk

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#167

One step at a time. Donā€™t like to mix too many items, esp the injections. My HbA1c has improved quite a bit from 11.9 two years ago to ~6.5 to 7.2 thus far. 4 readings below 7.0 is my next goal. My BMI is at 24.5 need to drop some more. Weight / visceral fat reduction to improve insulin sensitivity is my current focus. These activities have become a full time job! Cheers

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#168

Iā€™m having dental implants installed, so I am always interested in dental bone health and the impact of various medications. I have just initiated telmisartan 20mg/day, so this is interesting, but big caveat, this is in RATS.

Telmisartan Prevents Alveolar Bone Loss by Decreasing the Expression of Osteoclasts Markers in Hypertensive Rats With Periodontal Disease

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#169

Iā€™ll be trialling 40mg telmisartan. I was thinking of taking it at night. I have sleep apnea which can raise blood pressure. Taking it at night would be best for this?

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#170

Well, yes, I too am taking it at night. Itā€™s quite long lasting, so it doesnā€™t matter when you take it, it will be effective regardless, but taking it at night avoids any possible initial side effects like orthostatic hypotension, lightheadedness etc. Makes for a mch gentler introduction.

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#171

It might be best to take steps to treat your sleep apnea (if you havenā€™t already done so.) Sleep apnea is strongly correlated with atrial fibrillation.

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#172

I do. I use CPAP. I take tirzepatide. Iā€™m very lean. I still have it unfortunately.

Do you know of any other things I could do for this?

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#173

Breathing trainer THE BREATHER - Combined Respiratory Muscle Trainer

Itā€™s not approved for sleep apnea specifically, but inhaling and exhaling against resistance each has been shown in studies to improve sleep apnea (especially exhalation against resistance). This device does both.

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#174

Iā€™ve got.something like this. I should use it more frequently. My AHI is trending around 0.5 to 2 at the moment which is quite good. I just got over a cold which put it up to 4 to 7.

I think tirzepatide is working quite well.

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#175

Oldie but goodie. Review.

Should Angiotensin II Receptor Blockers and Statins Be Combined?

https://www.ahajournals.org/doi/10.1161/01.cir.0000139857.85424.45

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#176

In some cases surgery may help, if appropriate. You could ask your GP/specialist.

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#177

Something I am considering, like maybe tonsillectomy or rhinoplasty could solve the issue permanently. Itā€™s some kind of anatomical issue if losing body fat doesnā€™t solve it.

Iā€™m lean to the point where I have veins visible in my lats and abs.

I also have a bit of asthma as well so these things interact to cause the issue to be worse. Iā€™ll keep using CPAP until Iā€™m 100% sure Iā€™ve solved it.

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#178

I think the answer to the OP is as much as you can take up to 80mg until your BP is too low. After 80mg there arenā€™t really any benefits but more risk.

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#179

The combo pill is great 80mg Telmisartan / 5mg Amlodipine

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